Coherence-contrast x-ray imaging - which detects changes in the degree of coherence caused by the placement of a sample in an x-ray interferometer - was developed for biomedical applications. Because the technique's sensitivity depends on the density gradient in the sample, it is particularly suitable for observing biomedical samples with large density differences, such as samples that include both biological soft tissue and bone. A measurement principle and method of this technique are described, and a fine coherence-contrast image of a mouse leg is given as an example result.
© 2005 Optical Society of America
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(170.7440) Medical optics and biotechnology : X-ray imaging
(340.7440) X-ray optics : X-ray imaging
(340.7450) X-ray optics : X-ray interferometry
Akio Yoneyama, Tohoru Takeda, Yoshinori Tsuchiya, Jin Wu, Thet-Thet Lwin, and Kazuyuki Hyodo, "Coherence-contrast x-ray imaging based on x-ray interferometry," Appl. Opt. 44, 3258-3261 (2005)