OSA's Digital Library

Applied Optics

Applied Optics


  • Vol. 44, Iss. 16 — Jun. 1, 2005
  • pp: 3258–3261

Coherence-contrast x-ray imaging based on x-ray interferometry

Akio Yoneyama, Tohoru Takeda, Yoshinori Tsuchiya, Jin Wu, Thet-Thet Lwin, and Kazuyuki Hyodo  »View Author Affiliations

Applied Optics, Vol. 44, Issue 16, pp. 3258-3261 (2005)

View Full Text Article

Enhanced HTML    Acrobat PDF (270 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Coherence-contrast x-ray imaging—which detects changes in the degree of coherence caused by the placement of a sample in an x-ray interferometer—was developed for biomedical applications. Because the technique’s sensitivity depends on the density gradient in the sample, it is particularly suitable for observing biomedical samples with large density differences, such as samples that include both biological soft tissue and bone. A measurement principle and method of this technique are described, and a fine coherence-contrast image of a mouse leg is given as an example result.

© 2005 Optical Society of America

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(170.7440) Medical optics and biotechnology : X-ray imaging
(340.7440) X-ray optics : X-ray imaging
(340.7450) X-ray optics : X-ray interferometry

Original Manuscript: September 21, 2004
Revised Manuscript: December 5, 2004
Manuscript Accepted: January 13, 2005
Published: June 1, 2005

Akio Yoneyama, Tohoru Takeda, Yoshinori Tsuchiya, Jin Wu, Thet-Thet Lwin, and Kazuyuki Hyodo, "Coherence-contrast x-ray imaging based on x-ray interferometry," Appl. Opt. 44, 3258-3261 (2005)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. A. Momose, J. Fukuda, “Phase-contrast radiographs of non-stained rat cerebellar specimen,” Med. Phys. 22, 375–380 (1995). [CrossRef] [PubMed]
  2. T. Takeda, A. Momose, Y. Itai, J. Wu, K. Hirano, “Phase-contrast imaging with synchrotron x-rays for cancer lesion,” Acad. Radiol. 2, 799–803 (1995). [CrossRef] [PubMed]
  3. U. Bonse, M. Hart, “An x-ray interferometer,” Appl. Phys. Lett. 6, 155–156 (1965). [CrossRef]
  4. A. Momose, “Demonstration of phase-contrast x-ray computed tomography using an x-ray interferometer,” Nucl. Instrum. Methods Phys. Res. A 352, 622–628 (1995). [CrossRef]
  5. A. Momose, T. Takeda, Y. Itai, K. Hirano, “Phase-contrast x-ray computed tomography for observing biological soft tissues,” Nat. Med. 2, 473–475 (1996). [CrossRef] [PubMed]
  6. F. Beckmann, U. Bonse, F. Busch, O. Gunnewig, “x-ray microtomography using phase contrast for the investigation of organic matter,” J. Comput. Assist. Tomogr. 21, 539–553 (1997). [CrossRef] [PubMed]
  7. T. Takeda, A. Momose, K. Hirano, S. Haraoka, T. Watanabe, Y. Itai, “Human carcinoma: early experience with phase-contrast x-ray CT with synchrotron radiation—comparative specimen study with optical microscopy,” Radiology 214, 298–301 (2000). [CrossRef] [PubMed]
  8. P. Becker, U. Bonse, “The skew-symmetric two-crystal x-ray interferometer,” J. Appl. Crystallogr. 7, 593–598 (1974). [CrossRef]
  9. A. Yoneyama, T. Takeda, Y. Tsuchiya, J. Wu, T. T. Lwin, A. Koizumi, K. Hyodo, Y. Itai, “A phase-contrast x-ray imaging system—with a 60 × 30 mm field of view—based on a skew-symmetric two-crystal x-ray interferometer,” Nucl. Instrum. Methods Phys. Res. A 523, 217–222 (2004). [CrossRef]
  10. A. Momose, T. Takeda, A. Yoneyama, I. Koyama, Y. Itai, “Wide-area phase-contrast x-ray imaging using large x-ray interferometers,” Nucl. Instrum. Methods Phys. Res. A 467, 917–920 (2001). [CrossRef]
  11. A. Yoneyama, T. Takeda, Y. Tsuchiya, J. Wu, T. T. Lwin, K. Hyodo, “Large-area phase-contrast x-ray imaging system using a two-crystal x-ray interferometer,” in Proceedings of The Eighth International Conference on Synchrotron Radiation Instrumentation (SRI2003), T. Warwick, J. Arthur, H. A. Padmore, J. Stohr, eds., Vol. 705 of AIP Conference Proceedings Series (American Institute of Physics, New York, 2004), pp. 1299–1302. [CrossRef]
  12. J. H. Bruning, D. R. Herriott, J. E. Gallagher, D. P. Rosenfeld, A. D. White, D. J. Brangaccio, “Digital wavefront measuring interferometer for testing optical surfaces and lenses,” Appl. Opt. 13, 2693–2703 (1974). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3
Fig. 4

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited