We believe that we have developed the narrowest optical-fiber Raman probe ever reported, 600 µm in total diameter, that can be inserted into coronary arteries. The selection of suitable optical fibers, filters, and a processing method is discussed. Custom-made filters attached to the front end of a probe eliminate the background Raman signals of the optical fiber itself. The experimental evaluation of various optical fibers is carried out for the selection of suitable fibers. Measurement of the Raman spectra of an atherosclerotic lesion of a rabbit artery in vitro demonstrates the excellent performance of the micro-Raman probe.
© 2005 Optical Society of America
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(120.4570) Instrumentation, measurement, and metrology : Optical design of instruments
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.5660) Medical optics and biotechnology : Raman spectroscopy
Yuichi Komachi, Hidetoshi Sato, Katsuo Aizawa, and Hideo Tashiro, "Micro-optical fiber probe for use in an intravascular Raman endoscope," Appl. Opt. 44, 4722-4732 (2005)