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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 44, Iss. 7 — Mar. 1, 2005
  • pp: 1188–1190

Harmonic phase-dispersion microscope with a Mach–Zehnder interferometer

Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Christopher Fang-Yen, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld  »View Author Affiliations


Applied Optics, Vol. 44, Issue 7, pp. 1188-1190 (2005)
http://dx.doi.org/10.1364/AO.44.001188


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Abstract

Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach–Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.

© 2005 Optical Society of America

OCIS Codes
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.3880) Medical optics and biotechnology : Medical and biological imaging

History
Original Manuscript: June 3, 2004
Revised Manuscript: October 20, 2004
Manuscript Accepted: October 20, 2004
Published: March 1, 2005

Citation
Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Christopher Fang-Yen, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld, "Harmonic phase-dispersion microscope with a Mach–Zehnder interferometer," Appl. Opt. 44, 1188-1190 (2005)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-44-7-1188

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