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Applied Optics

Applied Optics


  • Editor: James C. Wyant
  • Vol. 45, Iss. 3 — Jan. 20, 2006
  • pp: 489–494

Correction method for absorption-dependent signal enhancement by a liquid-core optical fiber

Dahu Qi and Andrew J. Berger  »View Author Affiliations

Applied Optics, Vol. 45, Issue 3, pp. 489-494 (2006)

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The enhancement of a dissolved chemical's Raman scattering by a liquid-core optical fiber (LCOF) geometry is absorption dependent. This dependence leads to a disruption of the usual linear correlation between chemical concentration and Raman peak area. To recover the linearity, we augmented a standard LCOF Raman spectroscopy system with spectrophotometric capabilities, permitting sequential measurements of Raman and absorption spectra within the LCOF. Measurements of samples with identical Raman-scatterer concentrations but different absorption coefficients are described. Using the absorption values, we reduced variations in the measured Raman intensities from 60 % to less than 1 % . This correction method should be important for LCOF-based Raman spectroscopy of sample sets with variable absorption coefficients, such as urine and blood serum from multiple patients.

© 2006 Optical Society of America

OCIS Codes
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(300.6450) Spectroscopy : Spectroscopy, Raman

ToC Category:

Virtual Issues
Vol. 1, Iss. 2 Virtual Journal for Biomedical Optics

Dahu Qi and Andrew J. Berger, "Correction method for absorption-dependent signal enhancement by a liquid-core optical fiber," Appl. Opt. 45, 489-494 (2006)

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