Significance of tissue anisotropy in optical tomography of the infant brain
Applied Optics, Vol. 46, Issue 10, pp. 1633-1640 (2007)
http://dx.doi.org/10.1364/AO.46.001633
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Abstract
We study the effect of tissue anisotropy in optical tomography of neonates. A Monte Carlo method capable of modeling photon migration in an arbitrary 3D tissue model with spatially varying optical properties and tissue anisotropy is used for simulating measurements of neonates. Anatomical and diffusion tensor magnetic resonance imaging of neonates are used for creating the anatomical models. We find that tissue anisotropy affects the measured signal and the pattern of sensitivity in optical measurements.
© 2007 Optical Society of America
OCIS Codes
(170.5280) Medical optics and biotechnology : Photon migration
(170.6960) Medical optics and biotechnology : Tomography
ToC Category:
Diffuse optical imaging
History
Original Manuscript: July 3, 2006
Manuscript Accepted: August 10, 2006
Published: March 13, 2007
Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics
Citation
Juha Heiskala, Tuomas Neuvonen, P. Ellen Grant, and Ilkka Nissilä, "Significance of tissue anisotropy in optical tomography of the infant brain," Appl. Opt. 46, 1633-1640 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-10-1633
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