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Applied Optics

Applied Optics


  • Editor: James C. Wyant
  • Vol. 46, Iss. 10 — Apr. 1, 2007
  • pp: 1658–1668

Effect of probe arrangement on reproducibility of images by near-infrared topography evaluated by a virtual head phantom

Hiroshi Kawaguchi, Tatsuya Koyama, and Eiji Okada  »View Author Affiliations

Applied Optics, Vol. 46, Issue 10, pp. 1658-1668 (2007)

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The effect of the probe arrangement on the reproducibility of topographic images of the concentration changes in oxygenated hemoglobin and deoxygenated hemoglobin is evaluated by a virtual head phantom. A virtual head phantom consists of five types of tissue the 3D structure of which is based on a magnetic resonance imaging scan of an adult head. Localized and broadened brain activation is assumed in a virtual head phantom. The topographic images are obtained from the reflectance detected by the standard probe arrangement and the double-density probe arrangement. The uneven thickness of the superficial layer, which cannot be evaluated by the previous slab model, affects the distribution of measured activation in the topographic image, and this reduces the position reproducibility of near-infrared (NIR) topography with the standard probe arrangement. The overlapping measurements by the double-density probe arrangement can improve the reproducibility of the image obtained by NIR topography.

© 2007 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5280) Medical optics and biotechnology : Photon migration

ToC Category:
Diffuse optical imaging

Original Manuscript: July 3, 2006
Revised Manuscript: October 6, 2006
Manuscript Accepted: November 3, 2006
Published: March 13, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Hiroshi Kawaguchi, Tatsuya Koyama, and Eiji Okada, "Effect of probe arrangement on reproducibility of images by near-infrared topography evaluated by a virtual head phantom," Appl. Opt. 46, 1658-1668 (2007)

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