Image correction algorithm for functional three-dimensional diffuse optical tomography brain imaging
Applied Optics, Vol. 46, Issue 10, pp. 1693-1704 (2007)
http://dx.doi.org/10.1364/AO.46.001693
Enhanced HTML 
Acrobat PDF (2370 KB)
Abstract
We outline a computationally efficient image correction algorithm, which we have applied to diffuse optical tomography (DOT) image time series derived from a magnetic resonance imaging (MRI)-based brain model. Results show that the algorithm increases spatial resolution, decreases spatial bias, and only modestly reduces temporal accuracy for noise levels typically seen in experiment, and produces results comparable to image reconstructions that incorporate information from MRI priors. We demonstrate that this algorithm has robust performance in the presence of noise, background heterogeneity, irregular external and internal boundaries, and error in the initial guess. However, the algorithm introduces artifacts when the absorption and scattering coefficients of the reference medium are overestimated—a situation that is easily avoided in practice. The considered algorithm offers a practical approach to improving the quality of images from time-series DOT, even without the use of MRI priors.
© 2007 Optical Society of America
OCIS Codes
(100.1830) Image processing : Deconvolution
(100.2980) Image processing : Image enhancement
(100.6890) Image processing : Three-dimensional image processing
(100.6950) Image processing : Tomographic image processing
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
ToC Category:
Diffuse optical imaging
History
Original Manuscript: July 10, 2006
Revised Manuscript: November 7, 2006
Manuscript Accepted: November 8, 2006
Published: March 13, 2007
Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics
Citation
Yong Xu, Harry L. Graber, and Randall L. Barbour, "Image correction algorithm for functional three-dimensional diffuse optical tomography brain imaging," Appl. Opt. 46, 1693-1704 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-10-1693
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Inclusion Characterization in a Scattering Slab with Time-Resolved Transmittance Measurements: Perturbation Analysis (AO)
- Optical tomography using the SCIRun problem solving environment: Preliminary results for three-dimensional geometries and parallel processing (OE)
- Spatial deconvolution technique to improve the accuracy of reconstructed three-dimensional diffuse optical tomographic images (AO)
- Improved accuracy of reconstructed diffuse optical tomographic images by means of spatial deconvolution: two-dimensional quantitative characterization (AO)
- Image correction scheme applied to functional diffuse optical tomography scattering images (AO)
Related Conference Papers
- Long Exposure Point Spread Function Estimation from Adaptive Optics Loop Data
- Multiple-Experiment and Multiple-Physics Approaches for Fluorescence Guided Molecular Tomographic Imaging
- Towards Reconstruction of Embedded Objects with Multiple Spackle Images for Medical Diagnostics
- Suppression of scattering effect using spatially dependent point spread function
- Tomographic imaging of biological tissue by time-resolved, model-based, iterative image reconstruction
« Previous Article | Next Article »
OSA is a member of 