OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: James C. Wyant
  • Vol. 46, Iss. 10 — Apr. 1, 2007
  • pp: 1705–1716

Image correction scheme applied to functional diffuse optical tomography scattering images

Harry L. Graber, Yong Xu, and Randall L. Barbour  »View Author Affiliations


Applied Optics, Vol. 46, Issue 10, pp. 1705-1716 (2007)
http://dx.doi.org/10.1364/AO.46.001705


View Full Text Article

Enhanced HTML    Acrobat PDF (1425 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We have extended our investigation on the use of a linear algorithm for enhancing the accuracy of diffuse optical tomography (DOT) images, to include spatial maps of the diffusion coefficient. The results show that the corrected images are markedly improved in terms of estimated size, spatial resolution, two-object resolving power, and quantitative accuracy. These image-enhancing effects are significant at expected levels of diffusion-coefficient contrast in tissue and noise levels typical of experimental DOT data. Overall, the types and magnitudes of image-enhancing effects obtained here are qualitatively similar to those seen in previous studies on μ a perturbations. The implications for practical implementations of DOT time-series imaging are discussed.

© 2007 Optical Society of America

OCIS Codes
(100.1830) Image processing : Deconvolution
(100.2980) Image processing : Image enhancement
(100.6950) Image processing : Tomographic image processing
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Diffuse optical imaging

History
Original Manuscript: July 12, 2006
Revised Manuscript: November 16, 2006
Manuscript Accepted: November 27, 2006
Published: March 13, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Harry L. Graber, Yong Xu, and Randall L. Barbour, "Image correction scheme applied to functional diffuse optical tomography scattering images," Appl. Opt. 46, 1705-1716 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-10-1705


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. Y. Pei, H. L. Graber, and R. L. Barbour, "Influence of systematic errors in reference states on image quality and on stability of derived information for DC optical imaging," Appl. Opt. 40, 5755-5769 (2001). [CrossRef]
  2. S. R. Arridge and J. C. Hebden, "Optical imaging in medicine II: Modelling and reconstruction," Phys. Med. Biol. 42, 841-853 (1997). [CrossRef] [PubMed]
  3. R. L. Barbour, H. L. Graber, Y. Xu, Y. Pei, and R. Aronson, "Strategies for imaging diffusing media," Transp. Theory Stat. Phys. 33, 361-371 (2004). [CrossRef]
  4. H. L. Graber, Y. Xu, Y. Pei, and R. L. Barbour, "Spatial deconvolution technique to improve the accuracy of reconstructed three-dimensional diffuse optical tomographic images," Appl. Opt. 44, 941-953 (2005). [CrossRef] [PubMed]
  5. Y. Xu, H. L. Graber, Y. Pei, and R. L. Barbour, "Improved accuracy of reconstructed diffuse optical tomographic images by means of spatial deconvolution: two-dimensional quantitative characterization," Appl. Opt. 44, 2115-2139 (2005). [CrossRef] [PubMed]
  6. Y. Xu, Y. Pei, H. L. Graber, and R. L. Barbour, "Image quality improvement via spatial deconvolution in optical tomography: Time-series imaging," J. Biomed. Opt. 10, 051701 (2005). [CrossRef] [PubMed]
  7. D. W. McRobbie, E. A. Moore, M. J. Graves, and M. R. Prince, MRI from Picture to Proton, 2nd ed. (Cambridge U. Press, 2006.)
  8. Y. Xu, H. L. Graber, and R. L. Barbour, "Image correction algorithm for functional three-dimensional diffuse optical tomography brain imaging," Appl. Opt. 46, 1693-1704 (2007). [CrossRef] [PubMed]
  9. Y. Pei, H. L. Graber, and R. L. Barbour, "Normalized-constraint algorithm for minimizing inter-parameter cross talk in DC optical tomography," Opt. Express 9, 97-109 (2001). [CrossRef] [PubMed]
  10. H. L. Graber, Y. Pei, and R. L. Barbour, "Imaging of spatiotemporal coincident states by DC optical tomography," IEEE Trans. Med. Imaging 21, 852-866 (2002). [CrossRef] [PubMed]
  11. B. Chance, P. Cohen, F. Jöbsis, and B. Schoener, "Intracellular oxidation-reduction statesin vivo," Science 137, 499-508 (1962). [CrossRef] [PubMed]
  12. J. S. Maier, S. A. Walker, S. Fantini, M. A. Franceschini, and E. Gratton, "Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared," Opt. Lett. 19, 2062-2064 (1994). [CrossRef] [PubMed]
  13. B. W. Pogue, T. O. McBride, U. L. Osterberg, and K. D. Paulsen, "Comparison of imaging geometries for diffuse optical tomography of tissue," Opt. Express 4, 270-286 (1999). [CrossRef] [PubMed]
  14. A. P. Gibson, J. C. Hebden, and S. R. Arridge, "Recent advances in diffuse optical imaging," Phys. Med. Biol. 50, R1-R43 (2005). [CrossRef] [PubMed]
  15. D. Colton, H. W. Engl, A. K. Louis, J. R. McLaughlin, and W. Rundell, eds., Surveys on Solution Methods for Inverse Problems (Springer, 2000).
  16. A. N. Tikhonov and V. Y. Arsenin, Solutions of Ill-Posed Problems (V. H. Winston, 1977).
  17. P. Xu, "Truncated SVD methods for discrete linear ill-posed problems," Geophys. J. Int. 135, 505-514 (1998). [CrossRef]
  18. X. Gu, J. Masciotti, and A. H. Hielscher, "Parametric reconstruction method in optical tomography," in Proceedings of 28th IEEE EMBS Annual International Conference (IEEE, 2006), Paper FrB13.4.
  19. M. Huang and Q. Zhu, "Dual-mesh optical tomography reconstruction method with a depth correction that uses a priori ultrasound information," Appl. Opt. 43, 1654-1662 (2004). [CrossRef] [PubMed]
  20. M. J. Cassidy and W. D. Penny, "Bayesian nonstationary autoregressive models for biomedical signal analysis," IEEE Trans. Biomed. Eng. 49, 1142-1152 (2002). [CrossRef] [PubMed]
  21. R. L. Barbour, H. L. Graber, Y. Xu, Y. Pei, R. Ansari, M. B. Levin, and M. Farber, "Diffuse Optical Tissue Simulator (DOTS): An experimental calibrating system for functional DOT imaging," in Proceedings of Fifth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside (National Institutes of Health, 2006), Poster No. 76. [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited