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Applied Optics

Applied Optics


  • Editor: James C. Wyant
  • Vol. 46, Iss. 10 — Apr. 1, 2007
  • pp: 1705–1716

Image correction scheme applied to functional diffuse optical tomography scattering images

Harry L. Graber, Yong Xu, and Randall L. Barbour  »View Author Affiliations

Applied Optics, Vol. 46, Issue 10, pp. 1705-1716 (2007)

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We have extended our investigation on the use of a linear algorithm for enhancing the accuracy of diffuse optical tomography (DOT) images, to include spatial maps of the diffusion coefficient. The results show that the corrected images are markedly improved in terms of estimated size, spatial resolution, two-object resolving power, and quantitative accuracy. These image-enhancing effects are significant at expected levels of diffusion-coefficient contrast in tissue and noise levels typical of experimental DOT data. Overall, the types and magnitudes of image-enhancing effects obtained here are qualitatively similar to those seen in previous studies on μ a perturbations. The implications for practical implementations of DOT time-series imaging are discussed.

© 2007 Optical Society of America

OCIS Codes
(100.1830) Image processing : Deconvolution
(100.2980) Image processing : Image enhancement
(100.6950) Image processing : Tomographic image processing
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Diffuse optical imaging

Original Manuscript: July 12, 2006
Revised Manuscript: November 16, 2006
Manuscript Accepted: November 27, 2006
Published: March 13, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Harry L. Graber, Yong Xu, and Randall L. Barbour, "Image correction scheme applied to functional diffuse optical tomography scattering images," Appl. Opt. 46, 1705-1716 (2007)

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