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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: James C. Wyant
  • Vol. 46, Iss. 10 — Apr. 1, 2007
  • pp: 1795–1808

Multiscan time-domain optical coherence tomography for retina imaging

Carla Carmelo Rosa, John Rogers, Justin Pedro, Richard Rosen, and Adrian Podoleanu  »View Author Affiliations


Applied Optics, Vol. 46, Issue 10, pp. 1795-1808 (2007)
http://dx.doi.org/10.1364/AO.46.001795


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Abstract

A versatile time-domain optical coherence tomography system is presented that can generate cross-sectional images by using either transverse priority or depth priority scanning. This is made possible by using a transmissive scanning delay line compatible with balance detection operating at a speed similar to that of the transverse scanner used to scan the beam across the target. In vivo images from the retina are generated and shown using the same system switched to either transverse or depth priority scanning regime, by using the scanning delay line either in slow or fast scanning modes, respectively. A comparative analysis of different scanning regimes depending on image size to fit different areas to be imaged is presented. Safety thresholds due to the different continuous irradiation time per transverse pixel in different scanning regimes are also considered. We present the maximum exposure level for a variety of scanning procedures, employing either A scanning (depth priority) or T scanning (transverse priority) when generating cross-sectional images, en face images, or collecting 3D volumes.

© 2007 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(180.5810) Microscopy : Scanning microscopy

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: July 10, 2006
Revised Manuscript: November 14, 2006
Manuscript Accepted: December 18, 2006
Published: March 13, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Carla Carmelo Rosa, John Rogers, Justin Pedro, Richard Rosen, and Adrian Podoleanu, "Multiscan time-domain optical coherence tomography for retina imaging," Appl. Opt. 46, 1795-1808 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-10-1795

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