OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: James C. Wyant
  • Vol. 46, Iss. 16 — Jun. 1, 2007
  • pp: 3352–3358

Photoacoustic tomography using a Mach–Zehnder interferometer as an acoustic line detector

Guenther Paltauf, Robert Nuster, Markus Haltmeier, and Peter Burgholzer  »View Author Affiliations


Applied Optics, Vol. 46, Issue 16, pp. 3352-3358 (2007)
http://dx.doi.org/10.1364/AO.46.003352


View Full Text Article

Enhanced HTML    Acrobat PDF (550 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

A three-dimensional photoacoustic imaging method is presented that uses a Mach–Zehnder interferometer for measurement of acoustic waves generated in an object by irradiation with short laser pulses. The signals acquired with the interferometer correspond to line integrals over the acoustic wave field. An algorithm for reconstruction of a three-dimensional image from such signals measured at multiple positions around the object is shown that is a combination of a frequency-domain technique and the inverse Radon transform. From images of a small source scanning across the interferometer beam it is estimated that the spatial resolution of the imaging system is in the range of 100 to about 300 μ m , depending on the interferometer beam width and the size of the aperture formed by the scan length divided by the source–detector distance. By taking an image of a phantom it could be shown that the imaging system in its present configuration is capable of producing three-dimensional images of objects with an overall size in the range of several millimeters to centimeters. Strategies are proposed how the technique can be scaled for imaging of smaller objects with higher resolution.

© 2007 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(110.6960) Imaging systems : Tomography

ToC Category:
Imaging Systems

History
Original Manuscript: May 22, 2006
Revised Manuscript: December 14, 2006
Manuscript Accepted: January 2, 2007
Published: May 15, 2007

Virtual Issues
Vol. 2, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Guenther Paltauf, Robert Nuster, Markus Haltmeier, and Peter Burgholzer, "Photoacoustic tomography using a Mach-Zehnder interferometer as an acoustic line detector," Appl. Opt. 46, 3352-3358 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-16-3352


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. G. Ku, X. D. Wang, G. Stoica, and L.-H. V. Wang, "Multiple-bandwidth photoacoustic tomography," Phys. Med. Biol. 49, 1329-1338 (2004). [CrossRef] [PubMed]
  2. H. Schoeffmann, H. Schmidt-Kloiber, and E. Reichel, "Time-resolved investigations of laser-induced shock waves in water by use of polyvinylidenefluoride hydrophones," J. Appl. Phys. 63, 46-51 (1988). [CrossRef]
  3. Paul C. Beard, Andrew M. Hurrell, and Tim N. Mills, "Characterization of a polymer film optical fiber hydrophone for use in the range 1 to 20 MHz: a comparison with PVDF needle and membrane hydrophones," IEEE Trans. Ultrason. Ferroelect., Freq. Control 47, 256-264 (2000). [CrossRef]
  4. G. Paltauf and H. Schmidt-Kloiber, "Measurement of laser-induced acoustic waves with a calibrated optical transducer," J. Appl. Phys. 82, 1525-1531 (1997). [CrossRef]
  5. M. H. Xu, Y. Xu, and L.-H. V. Wang, "Time-domain reconstruction-algorithms and numerical simulations for thermoacoustic tomography in various geometries," IEEE Trans. Biomed. Eng. 50, 1086-1099 (2003). [CrossRef] [PubMed]
  6. K. P. Kostli, D. Frauchiger, J. J. Niederhauser, G. Paltauf, H. P. Weber, and M. Frenz, "Optoacoustic imaging using a three-dimensional reconstruction algorithm," IEEE J. Sel. Top. Quantum Electron. 7, 918-923 (2001). [CrossRef]
  7. G. Paltauf, J. A. Viator, S. A. Prahl, and S. L. Jacques, "Iterative reconstruction algorithm for optoacoustic imaging," J. Acoust. Soc. Am. 112, 1536-1544 (2002). [CrossRef] [PubMed]
  8. R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, "Thermoacoustic computed tomography using a conventional linear transducer array," Med. Phys. 30, 856-860 (2003). [CrossRef] [PubMed]
  9. A. A. Karabutov, E. V. Savateeva, and A. A. Oraevsky, "Optoacoustic tomography: new modality of laser diagnostic systems," Laser Phys. 13, 711-723 (2003).
  10. X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L.-H. V. Wang, "Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain," Nat. Biotechnol. 21, 803-806 (2003). [CrossRef] [PubMed]
  11. K. P. Kostli, M. Frenz, H. Bebie, and H. P. Weber, "Temporal backward projection of optoacoustic pressure transients using Fourier transform methods," Phys. Med Biol. 46, 1863-1872 (2001). [CrossRef] [PubMed]
  12. Y. Xu, D. Z. Feng, and L.-H. V. Wang, "Exact frequency-domain reconstruction for thermoacoustic tomography-I: planar geometry," IEEE Trans. Med. Imaging 21, 823-828 (2002). [CrossRef] [PubMed]
  13. M. H. Xu and L.-H. V. Wang, "Analytic explanation of spatial resolution related to bandwidth and detector aperture size in thermoacoustic or photoacoustic reconstruction," Phys. Rev. E 67, 056605 (2003). [CrossRef]
  14. M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, "Thermoacoustic computed tomography with large planar receivers," Inverse Probl. 20, 1663-1673 (2004). [CrossRef]
  15. P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, "Thermoacoustic tomography with integrating area and line detectors," IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577-1583 (2005). [CrossRef]
  16. M. Jaeger, J. J. Niederhauser, M. Hejazi, and M. Frenz, "Diffraction-free acoustic detection for optoacoustic depth profiling of tissue using an optically transparent polyvinylidene fluoride pressure transducer operated in backward and forward mode," J. Biomed. Opt. 10, 024035 (2005). [CrossRef] [PubMed]
  17. G. J. Diebold and T. Sun, "Properties of photoacoustic waves in one, two, and three dimensions," Acustica 80, 339-351 (1994).
  18. V. A. Shutilov, Fundamental Physics of Ultrasound (Gordon and Breach, 1988).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited