Monte Carlo modeling of optoacoustic signals from human internal jugular veins
Applied Optics, Vol. 46, Issue 21, pp. 4820-4827 (2007)
http://dx.doi.org/10.1364/AO.46.004820
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Abstract
Monitoring of blood oxygenation, in particular, cerebral venous oxygenation, is necessary for management of a variety of life-threatening conditions. An optoacoustic technique can be used for noninvasive monitoring of blood oxygenation in blood vessels, including large veins. We calculated optoacoustic signals from a cylinder mimicking a blood vessel using a modified Monte Carlo code and analyzed their temporal profiles. The rate of decrease of the integrated optoacoustic signal at different wavelengths of incident near-infrared radiation was related to the effective attenuation coefficient of normally oxygenated venous blood. We obtained good correlation of this parameter with the blood effective attenuation coefficient in a wide spectral range that may be useful in providing an accurate and robust optoacoustic monitoring of blood oxygenation. We also estimated the accuracy of effective attenuation coefficient calculations.
© 2007 Optical Society of America
OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.1460) Medical optics and biotechnology : Blood gas monitoring
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: August 2, 2006
Revised Manuscript: February 14, 2007
Manuscript Accepted: March 26, 2007
Published: July 6, 2007
Virtual Issues
Vol. 2, Iss. 8 Virtual Journal for Biomedical Optics
Citation
Igor Patrikeev, Yuriy Y. Petrov, Irina Y. Petrova, Donald S. Prough, and Rinat O. Esenaliev, "Monte Carlo modeling of optoacoustic signals from human internal jugular veins," Appl. Opt. 46, 4820-4827 (2007)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-46-21-4820
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