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Applied Optics

Applied Optics


  • Editor: James C. Wyant
  • Vol. 47, Iss. 12 — Apr. 20, 2008
  • pp: 2061–2069

Laser Doppler blood flow complementary metal oxide semiconductor imaging sensor with analog on-chip processing

Quan Gu, Barrie R. Hayes-Gill, and Stephen P. Morgan  »View Author Affiliations

Applied Optics, Vol. 47, Issue 12, pp. 2061-2069 (2008)

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A 4 × 4 pixel array with analog on-chip processing has been fabricated within a 0.35 μm complementary metal oxide semiconductor process as a prototype sensor for laser Doppler blood flow imaging. At each pixel the bandpass and frequency weighted filters necessary for processing laser Doppler blood flow signals have been designed and fabricated. Because of the space constraints of implementing an accurate ω 0.5 filter at the pixel level, this has been approximated using the “roll off” of a high-pass filter with a cutoff frequency set at 10 kHz . The sensor has been characterized using a modulated laser source. Fixed pattern noise is present that is demonstrated to be repeatable across the array and can be calibrated. Preliminary blood flow results on a finger before and after occlusion demonstrate that the sensor array provides the potential for a system that can be scaled to a larger number of pixels for blood flow imaging.

© 2008 Optical Society of America

OCIS Codes
(040.0040) Detectors : Detectors
(110.0110) Imaging systems : Imaging systems
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: December 3, 2007
Manuscript Accepted: February 10, 2008
Published: April 16, 2008

Virtual Issues
Vol. 3, Iss. 5 Virtual Journal for Biomedical Optics

Quan Gu, Barrie R. Hayes-Gill, and Stephen P. Morgan, "Laser Doppler blood flow complementary metal oxide semiconductor imaging sensor with analog on-chip processing," Appl. Opt. 47, 2061-2069 (2008)

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