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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: James C. Wyant
  • Vol. 47, Iss. 17 — Jun. 10, 2008
  • pp: 3152–3157

Half-ball lens couples a beveled fiber probe for depth-resolved spectroscopy: Monte Carlo simulations

Franck Jaillon, Wei Zheng, and Zhiwei Huang  »View Author Affiliations


Applied Optics, Vol. 47, Issue 17, pp. 3152-3157 (2008)
http://dx.doi.org/10.1364/AO.47.003152


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Abstract

In this study, we propose a beveled fiber-optic probe coupled with a half-ball lens for improving the depth-resolved fluorescence measurements of epithelial tissue. The Monte Carlo (MC) simulation results show that for a given excitation-collection fiber separation, the probe design with a bevel-angled collection fiber is more sensitive to detect fluorescence photons emitted from the shallow layer of tissue, whereas the flat-tip collection fiber is in favor of probing fluorescence photons originating from deeper tissue areas. This compact half-ball lens-beveled fiber probe design has the potential to facilitate the depth-resolved fluorescence detection of epithelial tissue.

© 2008 Optical Society of America

OCIS Codes
(060.2310) Fiber optics and optical communications : Fiber optics
(120.4570) Instrumentation, measurement, and metrology : Optical design of instruments
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(080.5692) Geometric optics : Ray trajectories in inhomogeneous media

ToC Category:
Fiber Optics and Optical Communications

History
Original Manuscript: January 31, 2008
Revised Manuscript: April 28, 2008
Manuscript Accepted: May 2, 2008
Published: June 2, 2008

Virtual Issues
Vol. 3, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Franck Jaillon, Wei Zheng, and Zhiwei Huang, "Half-ball lens couples a beveled fiber probe for depth-resolved spectroscopy: Monte Carlo simulations," Appl. Opt. 47, 3152-3157 (2008)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-47-17-3152

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