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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: Joseph N. Mait
  • Vol. 48, Iss. 18 — Jun. 20, 2009
  • pp: 3490–3496

Simple two-layer reflectance model for biological tissue applications

George Mantis and George Zonios  »View Author Affiliations


Applied Optics, Vol. 48, Issue 18, pp. 3490-3496 (2009)
http://dx.doi.org/10.1364/AO.48.003490


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Abstract

A two-layer tissue diffuse reflectance model is described. The model is based on a simple one-layer model that we have recently developed and successfully applied to the analysis of in vivo skin reflectance. The model, which is specifically designed for use with a fiber optic probe, has as its main features simplicity and ease of application, and it is capable of estimating the thickness and the absorption coefficient of a superficial absorbing and scattering layer. Both of these parameters are of great interest for the noninvasive study of epithelial biological tissues. The validity range and accuracy of the model are tested on tissue phantoms in both the forward and inverse modes of application.

© 2009 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 11, 2009
Revised Manuscript: April 30, 2009
Manuscript Accepted: June 3, 2009
Published: June 12, 2009

Virtual Issues
Vol. 4, Iss. 8 Virtual Journal for Biomedical Optics

Citation
George Mantis and George Zonios, "Simple two-layer reflectance model for biological tissue applications," Appl. Opt. 48, 3490-3496 (2009)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-48-18-3490


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