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Applied Optics

Applied Optics


  • Editor: Joseph N. Mait
  • Vol. 50, Iss. 25 — Sep. 1, 2011
  • pp: 5031–5041

Enhancing finite element-based photoacoustic tomography using total variation minimization

Lei Yao and Huabei Jiang  »View Author Affiliations

Applied Optics, Vol. 50, Issue 25, pp. 5031-5041 (2011)

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A total variation minimization (TVM)-based finite element reconstruction algorithm for photoacoustic (PA) tomography is described in this paper. This algorithm is used to enhance the quality of reconstructed PA images with time-domain data. Simulations are conducted where different contrast levels between the target and the background, different noise levels, and different sizes and shapes of the target are studied in a 30 mm diameter circular heterogeneous background. These simulated results show that the quality of the reconstructed images can be improved significantly due to the decreased sensitivity to noise effect when the TVM is included in the reconstruction algorithm. The enhancement is further confirmed using experimental data obtained from several phantom experiments and an in vivo animal experiment.

© 2011 Optical Society of America

OCIS Codes
(100.2980) Image processing : Image enhancement
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Image Processing

Original Manuscript: May 27, 2011
Manuscript Accepted: July 25, 2011
Published: August 30, 2011

Virtual Issues
Vol. 6, Iss. 10 Virtual Journal for Biomedical Optics

Lei Yao and Huabei Jiang, "Enhancing finite element-based photoacoustic tomography using total variation minimization," Appl. Opt. 50, 5031-5041 (2011)

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