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Partially coherent lensfree tomographic microscopy [Invited] |
Applied Optics, Vol. 50, Issue 34, pp. H253-H264 (2011)
http://dx.doi.org/10.1364/AO.50.00H253
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Abstract
Optical sectioning of biological specimens provides detailed volumetric information regarding their internal structure. To provide a complementary approach to existing three-dimensional (3D) microscopy modalities, we have recently demonstrated lensfree optical tomography that offers high-throughput imaging within a compact and simple platform. In this approach, in-line holograms of objects at different angles of partially coherent illumination are recorded using a digital sensor-array, which enables computing pixel super-resolved tomographic images of the specimen. This imaging modality, which forms the focus of this review, offers micrometer-scale 3D resolution over large imaging volumes of, for example,
© 2011 Optical Society of America
OCIS Codes
(110.0180) Imaging systems : Microscopy
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy
(110.1758) Imaging systems : Computational imaging
(090.1995) Holography : Digital holography
(110.6955) Imaging systems : Tomographic imaging
ToC Category:
Invited ISP Papers
History
Original Manuscript: August 1, 2011
Revised Manuscript: October 11, 2011
Manuscript Accepted: October 11, 2011
Published: December 5, 2011
Virtual Issues
Vol. 7, Iss. 2 Virtual Journal for Biomedical Optics
Digital Holography and 3D Imaging 2011 (2011) Applied Optics
Citation
Serhan O. Isikman, Waheb Bishara, and Aydogan Ozcan, "Partially coherent lensfree tomographic microscopy [Invited]," Appl. Opt. 50, H253-H264 (2011)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-50-34-H253
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