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Applied Optics

Applied Optics


  • Editor: Joseph N. Mait
  • Vol. 52, Iss. 12 — Apr. 20, 2013
  • pp: 2711–2717

Optical profiles of cathode ray tube and liquid crystal display monitors: implication in cutaneous phototoxicity in photodynamic therapy

Tim C. Lei, Srinivas Pendyala, Larry Scherrer, Buhong Li, Gregory F. Glazner, and Zheng Huang  »View Author Affiliations

Applied Optics, Vol. 52, Issue 12, pp. 2711-2717 (2013)

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Recent clinical reports suggest that overexposure to light emissions generated from cathode ray tube (CRT) and liquid crystal display (LCD) color monitors after topical or systemic administration of a photosensitizer could cause noticeable skin phototoxicity. In this study, we examined the light emission profiles (optical irradiance, spectral irradiance) of CRT and LCD monitors under simulated movie and video game modes. Results suggest that peak emissions and integrated fluence generated from monitors are clinically relevant and therefore prolonged exposure to these light sources at a close distance should be avoided after the administration of a photosensitizer or phototoxic drug.

© 2013 Optical Society of America

OCIS Codes
(170.1870) Medical optics and biotechnology : Dermatology
(170.5180) Medical optics and biotechnology : Photodynamic therapy
(230.3670) Optical devices : Light-emitting diodes

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: February 1, 2013
Revised Manuscript: February 1, 2013
Manuscript Accepted: March 6, 2013
Published: April 16, 2013

Virtual Issues
Vol. 8, Iss. 5 Virtual Journal for Biomedical Optics

Tim C. Lei, Srinivas Pendyala, Larry Scherrer, Buhong Li, Gregory F. Glazner, and Zheng Huang, "Optical profiles of cathode ray tube and liquid crystal display monitors: implication in cutaneous phototoxicity in photodynamic therapy," Appl. Opt. 52, 2711-2717 (2013)

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  1. G. M. Murphy, “Diseases associated with photosensitivity,” J. Photochem. Photobiol. B 64, 93–98 (2001). [CrossRef]
  2. R. Roelandts, “The diagnosis of photosensitivity,” Arch. Derm. 136, 1152–1157 (2000). [CrossRef]
  3. S. S. Yashar and H. W. Lim, “Classification and evaluation of photodermatoses,” Derm. Ther. 16, 1–7 (2003). [CrossRef]
  4. G. Vassileva, G. Mateev, and L. C. Parish, “Antimicrobial photosensitive reactions,” Arch. Intern. Med. 158, 1993–2000(1998). [CrossRef]
  5. Z. Huang, “A review of progress in clinical photodynamic therapy,” Technol. Cancer Res. Treat. 4, 283–293 (2005).
  6. E. Bromley, B. Briggs, L. Keltner, and S. S. Wang, “Characterization of cutaneous photosensitivity in healthy volunteers receiving talaporfin sodium,” Photoderm. Photoimmun. Photomed. 27, 85–89 (2011). [CrossRef]
  7. X. Wang, H. Wang, and Z. Huang, “Photosensitization induced by exposure to colour cathode ray tube monitor following topical 5-aminolaevulinic acid-based photodynamic therapy: a case report,” Acta Derm. Vener. 90, 545–547 (2010). [CrossRef]
  8. K. H. Yuan, J. H. Gao, and Z. Huang, “Adverse effects associated with photodynamic therapy (PDT) of port-wine stain (PWS) birthmarks,” Photodiagn. Photodyn. Ther. 9, 332–336 (2012). [CrossRef]
  9. A. Lesar, J. Ferguson, and H. Moseley, “An investigation of the fluorescence induced by topical application of 5-aminolaevulinic acid and methyl aminolaevulinate at different body sites on normal human skin,” Photodiagn. Photodyn. Ther. 8, 97–103 (2011). [CrossRef]
  10. W. G. Roberts, K. M. Smith, J. L. McCullough, and M. W. Berns, “Skin photosensitivity and photodestruction of several potential photodynamic sensitizers,” Photochem. Photobiol. 49, 431–438 (1989). [CrossRef]
  11. J. L. Sandell and T. C. Zhu, “A review of in-vivo optical properties of human tissues and its impact on PDT,” J. Biophoton. 4, 773–787 (2011). [CrossRef]
  12. R. R. Allison, G. H. Downie, R. Cuenca, X. Hu, C. J. H. Childs, and C. H. Sibata, “Photosensitizers in clinical PDT,” Photodiagn. Photodyn. Ther. 1, 27–42 (2004). [CrossRef]
  13. T. C. Lei, G. F. Glazner, M. Duffy, L. Scherrer, S. Pendyala, B. H. Li, X. L. Wang, H. W. Wang, and Z. Huang, “Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer,” Photodiagn. Photodyn. Ther. 9, 232–242 (2012). [CrossRef]
  14. J. J. Hunter, J. I. Morgan, W. H. Merigan, D. H. Sliney, J. R. Sparrow, and D. R. Williams, “The susceptibility of the retina to photochemical damage from visible light,” Prog. Retinal Eye Res. 31, 28–42 (2012). [CrossRef]

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