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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Editor: Joseph N. Mait
  • Vol. 52, Iss. 29 — Oct. 10, 2013
  • pp: 7206–7213

Computational study of a label-free biosensor based on a photonic crystal nanocavity resonator

Saeed Olyaee and Samira Najafgholinezhad  »View Author Affiliations


Applied Optics, Vol. 52, Issue 29, pp. 7206-7213 (2013)
http://dx.doi.org/10.1364/AO.52.007206


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Abstract

In this paper, we demonstrate and theoretically investigate a compact two-dimensional (2D) photonic crystal biosensor implemented by a waveguide and cavity. Biomaterials such as DNA molecules and proteins trapped inside a hole cause resonant wavelength shifting at the output terminal. The quality factor and sensitivity were obtained at about 4000 and 1.63nm/fg, respectively. Also, we investigated this structure as a bulk refractive index sensor with a sensitivity of about 165.45nm/RIU (refractive index units). Then, we modified the structure as a multichannel biosensor. This biosensor has the capability of highly parallel operation because of special architecture that was obtained by lattice shifting of a single hole around the cavity. Each channel had a different resonant cavity wavelength and the filling of analyte in selected holes caused resonant wavelength shifting, independently. Plane wave expansion (PWE) and finite difference time domain (FDTD) methods were used to analyze and compute the sensor characteristics.

© 2013 Optical Society of America

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(160.1435) Materials : Biomaterials

ToC Category:
Remote Sensing and Sensors

History
Original Manuscript: July 12, 2013
Revised Manuscript: September 12, 2013
Manuscript Accepted: September 25, 2013
Published: October 10, 2013

Citation
Saeed Olyaee and Samira Najafgholinezhad, "Computational study of a label-free biosensor based on a photonic crystal nanocavity resonator," Appl. Opt. 52, 7206-7213 (2013)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-52-29-7206

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