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Applied Optics

Applied Optics


  • Editor: Joseph N. Mait
  • Vol. 52, Iss. 32 — Nov. 10, 2013
  • pp: 7806–7811

Detection of single gold nanoparticles using spatial modulation spectroscopy implemented with a galvo-scanning mirror system

Mary Sajini Devadas, Zhongming Li, Todd A. Major, Shun Shang Lo, Nicolas Havard, Kuai Yu, Paul Johns, and Gregory V. Hartland  »View Author Affiliations

Applied Optics, Vol. 52, Issue 32, pp. 7806-7811 (2013)

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The optical extinction of single nanoparticles can be sensitively detected by spatial modulation spectroscopy (SMS), where the particle is moved in and out of a tightly focused laser beam with a piezo-device. Here we show that high sensitivity can be obtained by modulating the beam with a galvo-mirror system, rather than by moving the sample. This work demonstrates an inexpensive method for making a SMS microscope, and shows how an existing laser scanning microscope can be adapted for SMS measurements. The galvo-mirror technique also allows SMS measurements to be performed in a liquid, which is difficult to do with piezo-modulation.

© 2013 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(300.1030) Spectroscopy : Absorption
(160.4236) Materials : Nanomaterials

ToC Category:

Original Manuscript: August 12, 2013
Revised Manuscript: October 16, 2013
Manuscript Accepted: October 17, 2013
Published: November 8, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Mary Sajini Devadas, Zhongming Li, Todd A. Major, Shun Shang Lo, Nicolas Havard, Kuai Yu, Paul Johns, and Gregory V. Hartland, "Detection of single gold nanoparticles using spatial modulation spectroscopy implemented with a galvo-scanning mirror system," Appl. Opt. 52, 7806-7811 (2013)

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