Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Synthesis of dye conjugates to visualize the cancer cells using fluorescence microscopy

Not Accessible

Your library or personal account may give you access

Abstract

The clinical diagnosis of most cancers is based on evaluation of histology microscopic slides to view the size and shape of cellular nuclei and morphological structure of tissue. To achieve this goal for in vivo and in-deep tissues, near infrared dyes-bovine serum albumin and immunoglobulin G conjugates were synthesized. The spectral study shows that the absorption and fluorescence of the dye conjugates are in the “tissue optical window” spectral ranges between 650 and 900 nm. The internalization and pinocytosis of the synthesized compounds were investigated at cell level using fluorescence microscopy to obtain the optimal concentration and staining time.

© 2014 Optical Society of America

Full Article  |  PDF Article
More Like This
Time-resolved fluorescence polarization dynamics and optical imaging of Cytate: a prostate cancer receptor-targeted contrast agent

Y. Pu, W. B. Wang, B. B. Das, S. Achilefu, and R. R. Alfano
Appl. Opt. 47(13) 2281-2289 (2008)

Human serum albumin gradient in serous ovarian cancer cryosections measured by fluorescence lifetime

Fangrui Lin, Chenshuang Zhang, Yanping Li, Junshuai Yan, Yunjian Xu, Ying Pan, Rui Hu, Liwei Liu, and Junle Qu
Biomed. Opt. Express 12(3) 1195-1204 (2021)

Hyperspectral microscopy combined with DAPI staining for the identification of hepatic carcinoma cells

Kunxing Liu, Sifan Lin, Siqi Zhu, Yao Chen, Hao Yin, Zhen Li, and Zhenqiang Chen
Biomed. Opt. Express 12(1) 173-180 (2021)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved