OSA's Digital Library

Applied Spectroscopy

Applied Spectroscopy

| PUBLISHED BY SAS — AVAILABLE FROM SAS AND OSA

  • Vol. 49, Iss. 4 — Apr. 1, 1995
  • pp: 432–436

Screening Pap Smears with Near-Infrared Spectroscopy

Zhengfang Ge, Chris W. Brown, and Harold J. Kisner

Applied Spectroscopy, Vol. 49, Issue 4, pp. 432-436 (1995)


View Full Text Article

Acrobat PDF (479 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations
  • Export Citation/Save Click for help

Abstract

A rapid method for the analysis of Pap smears has been developed with the use of near-infrared spectroscopy. Spectra of Pap smears from 50 female patients including 30 with normal cells, 9 with atypical cells, and 11 with cervical cancer were measured in the near-IR region of 4000 to 10,000 cm-1. Both the original spectra and the second-derivative spectra of Pap smears were subjected to data analysis. The malignant samples displayed abnormal spectra compared with the corresponding normal cervical samples; the atypical samples have spectral features characteristic of both normal and abnormal samples. With the use of principal component analysis (PCA) and discriminant analysis, the samples were grouped in patterns that were consistent with clinical analysis. Since obtaining near-infrared spectra of human tissues is a rapid and inexpensive process, the results suggest that the near-infrared spectra of human tissues may be of diagnostic value for cancer diagnosis.

Citation
Zhengfang Ge, Chris W. Brown, and Harold J. Kisner, "Screening Pap Smears with Near-Infrared Spectroscopy," Appl. Spectrosc. 49, 432-436 (1995)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-49-4-432

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited