Abstract

Near-infrared spectrometry is being applied in the solution of problems in many areas of biomedical and pharmaceutical research, including cardiovascular radiology, brain imaging, formulation, quality/process control, and even clinical trials. The technique can also play a role in the biotechnology industry in the nondestructive analysis of small quantities of expensive materials. This report first defines near-IR spectrometry and imaging and then describes its application to atherosclerosis and stroke research. New developments in near-IR optics and instrumentation that make effective biomedical near-IR spectrometry possible are related, and, finally, new computational research results in parallel supercomputing for near-IR imaging are described. Together, instrumentation, optics, and computing combine to poise biomedical near-IR spectrometry for great advances as it enters the next century.

Laser heating of dielectric particles for medical and biological applications

Michael I. Tribelsky and Yasuhide Fukumoto
Biomed. Opt. Express 7(7) 2781-2788 (2016)

Novel fluorescent probe for low density lipoprotein, based on the enhancement of Europium emission band

L. C. Courrol, A.M. Monteiro, F.R.O. Silva, L. Gomes, N.D. Vieira, M.A. Gidlund, and A.M. Figueiredo Neto
Opt. Express 15(11) 7066-7074 (2007)

Mid-infrared Lasers for Medical Applications: introduction to the feature issue

Fatima Toor, Stuart Jackson, Xiaoming Shang, Shamsul Arafin, and Haining Yang
Biomed. Opt. Express 9(12) 6255-6257 (2018)

Multi-channel medical device for time domain functional near infrared spectroscopy based on wavelength space multiplexing

Rebecca Re, Davide Contini, Massimo Turola, Lorenzo Spinelli, Lucia Zucchelli, Matteo Caffini, Rinaldo Cubeddu, and Alessandro Torricelli
Biomed. Opt. Express 4(10) 2231-2246 (2013)

Infrared spectrometry

George A. Vanasse
Appl. Opt. 21(2) 189-195 (1982)