OSA's Digital Library

Applied Spectroscopy

Applied Spectroscopy

| PUBLISHED BY SAS — AVAILABLE FROM SAS AND OSA

  • Vol. 11, Iss. 4 — Nov. 1, 1957
  • pp: 177–188

An Infrared Study of the Reaction of Barbiturates with p-Nitrobenzyl Chloride

Leslie G. Chatten and Leo Levi

Applied Spectroscopy, Vol. 11, Issue 4, pp. 177-188 (1957)


View Full Text Article

Acrobat PDF (840 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations
  • Export Citation/Save Click for help

Abstract

In alkaline media barbiturates of the general formula HNCONHCOCR'R"CO react with p-nitrobenzyl chloride to give derivatives of the composition NCONCOCH2 C6H2NO2CR'R"COCH2-C6H2NO2: It is postulated that the process of complex formation proceeds via the interaction of a negatively charged enolized barbituric acid ion with a positively charged p-nitrobenzyl ion. The infrared absorption spectra of the derivatives are in accord with this mechanism and suggest that in the complex the barbiturate is bonded to the p-nitrobenzyl money through the carbonyl oxygens in the 4 and 6 positions. The compounds show unique features throughout the region studied, 4000-650 cm−1, and hence the method affords a high degree of specificity for detecting and characterizing these sedative drugs.

Citation
Leslie G. Chatten and Leo Levi, "An Infrared Study of the Reaction of Barbiturates with p-Nitrobenzyl Chloride," Appl. Spectrosc. 11, 177-188 (1957)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-11-4-177


Sort:  Journal  |  Reset

References

References are not available for this paper.

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited