Abstract

Raman spectroscopy has been used increasingly to determine the conformation of the peptide backbone and the side chain microenvironment of some amino acid residues. Because of the relative uncertainty about the absolute magnitude of intensity, Raman spectroscopy has been used primarily for qualitative evaluation of properties of proteins. There have, however, been some attempts to use Raman spectroscopy for quantitative purposes in the analysis of protein conformations.

Nonlinear optical properties of aromatic amino acids in the femtosecond regime

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Waveguide-based surface-enhanced Raman spectroscopy detection of protease activity using non-natural aromatic amino acids

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Qualitative detection of amino acids in a mixture with terahertz spectroscopic imaging

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Age-related alterations in the diffusional transport of amino acids across the human Bruch’s-choroid complex

Ali A. Hussain, Lisa Rowe, and John Marshall
J. Opt. Soc. Am. A 19(1) 166-172 (2002)