Abstract

A photothermal deflection detector for microbore liquid chromatography is described. The detection limit of the system under isocratic flow conditions is shown to be 8 × 10⁻⁸ absorbance units. This corresponds to 500 fg of analyte (acid sulfonate rug dye) injected on the column. The detection system is shown to be amenable to gradient elution and open tubular chromatography.

Detector effects in photothermal deflection experiments

Dorota Korte Kobylińska, Roman J. Bukowski, Jerzy Bodzenta, Stanisław Kochowski, and Anna Kaźmierczak-Balata
Appl. Opt. 47(10) 1559-1566 (2008)

Characterization of some suitable deflecting liquids in photothermal deflection spectroscopy

Marco Montecchi and Enrico Masetti
Appl. Opt. 29(28) 3989-3990 (1990)

Performance of a photothermal detector with turbid liquids

Jane Hodgkinson, Mark Johnson, and John P. Dakin
Appl. Opt. 44(20) 4360-4367 (2005)

Sensitive photothermal deflection technique for measuring absorption in optically thin media

A. C. Boccara, D. Fournier, Warren Jackson, and Nabil M. Amer
Opt. Lett. 5(9) 377-379 (1980)

Photothermal deflection spectroscopy and detection

W. B. Jackson, N. M. Amer, A. C. Boccara, and D. Fournier
Appl. Opt. 20(8) 1333-1344 (1981)