Carbon13 chemical shift assignments are reported for Z- and E-dothiepin hydrochloride (N,N-dimethyldibenzo[b,e]thiepin-delta-11(6H)', gamma-propylamine hydrochloride). The commercial product, a mixture of approximately 95% E-isomer, is of clinical importance as an antide-pressant drug. The precursor and degradation product, 6H-dibenzo[b,e]thiepin-11-one, and related model compounds were also studied. Homo- and heteronuclear shift-correlated 2D NMR, selective INEPT, selective and off-resonance decoupling, and inversion-recovery (T1) experiments as well as model compound comparisons were used in assignments.
Dorothy K. Wyatt, Nina Matheny Roscher, and Lee T. Grady, "Carbon13 NMR Shift Assignments for E- and Z-Dothiepin Hydrochloride and 6H-Dibenzo[b,e]thiepin-11-One," Appl. Spectrosc. 40, 369-373 (1986)
References are not available for this paper.
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.