Protein adsorption (fluorescein labeled gamma globulin, FITC-IgG) on the surface of poly(styrene) thin-film optical waveguides was fluorescently detected. The time course of adsorption, the FITC-IgG fluorescence spectra, and the surface concentration estimates are presented. The results demonstrate the potential use of polymer optical waveguides as integrated optic evanescent sensors.
J. T. Ives and W. M. Reichert, "Protein Adsorption on the Surface of a Thin-Film Polymer Integrated Optical Waveguide," Appl. Spectrosc. 42, 68-72 (1988)