Abstract

Jorgenson and co-workers have reported the use of capillary zone electrophoresis for high-resolution separation of proteins and small molecules. The technique has been shown to provide separation efficiencies of more than 100,000 theoretical plates per meter. Achievement of this efficiency requires use of capillaries with diameters of 75 μm or less. The narrow bore is required to make heat transfer to the capillary walls sufficiently efficient to keep the electrolyte at constant temperature. The narrow bore generates problems, both in sample introduction and in detection.

On-column refractive-index detection based on retroreflected beam interference for capillary electrophoresis

Yanzhuo Deng and Bincheng Li
Appl. Opt. 37(6) 998-1005 (1998)

Terahertz-capillary electrophoresis (THz-CE) for direct detection of separated substances in solutions

Keiko Kitagishi, Takayuki Kawai, Masayoshi Tonouchi, and Kazunori Serita
Opt. Mater. Express 14(2) 472-482 (2024)

Laser-based refractive-index detection for capillary electrophoresis: ray-tracing interference theory

Beat Krattiger, Alfredo E. Bruno, H. Michael Widmer, Martial Geiser, and René Dändliker
Appl. Opt. 32(6) 956-965 (1993)

Light-emitting-diode-induced fluorescence detection of fluorescent dyes for capillary electrophoresis microchip with cross-polarization method

Xiaobo Yang, Weiping Yan, Zhihuan Liu, and Hongfeng Lv
Appl. Opt. 51(11) 1694-1700 (2012)

Laser-induced fluorescence detector with a fiber-coupled micro GRIN lens for capillary electrophoresis

Oluwatosin O. Dada
Appl. Opt. 59(16) 4849-4855 (2020)