A method has been developed for the determination of silicone in breast tissue samples using a graphite furnace continuum source atomic absorption spectrometer. Silicone was measured as Si present in a heptane extract of the dried tissue samples. Thirty tissue samples were examined from 16 women having silicone gel-filled breast implants. Concentrations of Si in the dried tissue samples ranged from below the method detection limit of 3 ppm, to 6%.
D. N. Wichems, Clifton P. Calloway, Reshan Fernando, Bradley T. Jones, and Michael J. Morykwas, "Determination of Silicone in Breast Tissue by Graphite Furnace Continuum Source Atomic Absorption Spectrometry," Appl. Spectrosc. 47, 1577-1579 (1993)