OSA's Digital Library

Applied Spectroscopy

Applied Spectroscopy

| PUBLISHED BY SAS — AVAILABLE FROM SAS AND OSA

  • Vol. 48, Iss. 4 — Apr. 1, 1994
  • pp: 477–483

Temperature-Insensitive Near-Infrared Spectroscopic Measurement of Glucose in Aqueous Solutions

Kevin H. Hazen, Mark A. Arnold, and Gary W. Small

Applied Spectroscopy, Vol. 48, Issue 4, pp. 477-483 (1994)


View Full Text Article

Acrobat PDF (777 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations
  • Export Citation/Save Click for help

Abstract

A digital Fourier filter is combined with partial least-squares (PLS) regression to generate a calibration model for glucose that is insensitive to sample temperature. This model is initially created by using spectra collected over the 5000 to 4000 cm-1 spectral range with samples maintained at 37°C. The analytical utility of the model is evaluated by judging the ability to determine glucose concentrations from a set of prediction spectra. Absorption spectra in this prediction set are obtained by ratioing single-beam spectra collected from solutions at temperatures ranging from 32 to 41°C to reference spectra collected at 37°C. The temperature sensitivity of the underlying water absorption bands creates large baseline variations in prediction spectra that are effectively eliminated by the Fourier filtering step. The best model provides a mean standard error of prediction across temperatures of 0.14 mM (2.52 mg/dL). The benefits of the Fourier filtering step are established, and critical experimental parameters, such as number of PLS factors, mean and standard deviation for the Gaussian shaped Fourier filter, and spectral range, are considered.

Citation
Kevin H. Hazen, Mark A. Arnold, and Gary W. Small, "Temperature-Insensitive Near-Infrared Spectroscopic Measurement of Glucose in Aqueous Solutions," Appl. Spectrosc. 48, 477-483 (1994)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-48-4-477


Sort:  Journal  |  Reset

References

References are not available for this paper.

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited