Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 49,
  • Issue 4,
  • pp. 432-436
  • (1995)

Screening Pap Smears with Near-Infrared Spectroscopy

Not Accessible

Your library or personal account may give you access

Abstract

A rapid method for the analysis of Pap smears has been developed with the use of near-infrared spectroscopy. Spectra of Pap smears from 50 female patients including 30 with normal cells, 9 with atypical cells, and 11 with cervical cancer were measured in the near-IR region of 4000 to 10,000 cm<sup>-1</sup>. Both the original spectra and the second-derivative spectra of Pap smears were subjected to data analysis. The malignant samples displayed abnormal spectra compared with the corresponding normal cervical samples; the atypical samples have spectral features characteristic of both normal and abnormal samples. With the use of principal component analysis (PCA) and discriminant analysis, the samples were grouped in patterns that were consistent with clinical analysis. Since obtaining near-infrared spectra of human tissues is a rapid and inexpensive process, the results suggest that the near-infrared spectra of human tissues may be of diagnostic value for cancer diagnosis.

PDF Article
More Like This
Distinction of cervical cancer biopsies by use of infrared microspectroscopy and probabilistic neural networks

A. Podshyvalov, R. K. Sahu, S. Mark, K. Kantarovich, H. Guterman, J. Goldstein, R. Jagannathan, S. Argov, and S. Mordechai
Appl. Opt. 44(18) 3725-3734 (2005)

Optically computing the hit–miss transform for an automated cervical smear screening system

John L. Metz and Kristina M. Johnson
Appl. Opt. 39(5) 803-813 (2000)

Rapid detection of hysteromyoma and cervical cancer based on serum surface-enhanced Raman spectroscopy and a support vector machine

Xiangxiang Zheng, Guohua Wu, Jing Wang, Longfei Yin, and Xiaoyi Lv
Biomed. Opt. Express 13(4) 1912-1923 (2022)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved