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Applied Spectroscopy

Applied Spectroscopy

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  • Vol. 49, Iss. 4 — Apr. 1, 1995
  • pp: 540–541

Transmission FT-IR Spectroscopy Applied to the Determination of Hydrocarbon Residues on Pharmaceutical Process Equipment

Anthony G. Severdia

Applied Spectroscopy, Vol. 49, Issue 4, pp. 540-541 (1995)


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Abstract

In the course of operating process equipment in the pharmaceutical industry, it is necessary to assure that all product contact surfaces of process equipment contain a minimum amount of residue. The residue may be another product remaining from a previous operation, an excipient, or a "nonformulation" type of material. This report discusses the determination of hydrocarbons, in the form of lubricating greases, on the product contact surface of various tablet presses by use of FT-IR spectroscopy. The FT-IR spectroscopic method provides for both identification and quantitation of the lubricant and was suggested by an EPA method.

Citation
Anthony G. Severdia, "Transmission FT-IR Spectroscopy Applied to the Determination of Hydrocarbon Residues on Pharmaceutical Process Equipment," Appl. Spectrosc. 49, 540-541 (1995)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-49-4-540


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