Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 50,
  • Issue 12,
  • pp. 1471-1478
  • (1996)

Tools for Combinatorial Chemistry: In Situ Infrared Analysis of Solid-Phase Organic Reactions

Not Accessible

Your library or personal account may give you access

Abstract

Methodology for <i>in situ</i> infrared monitoring and analysis of solid-phase organic reactions has been developed. The real-time, single-bead capabilities of this technique are illustrated through the analysis of solvent diffusion into, and subsequent wash-out from, a 70-μm aminomethyl polystyrene bead. This report further illustrates application of this technology for solid-phase synthesis with real-time analysis using two example reactions. Analytical hardware and the inherent benefits of real-time analysis with respect to precursor referencing and the quality, utility, and interpretation of the infrared data are also discussed.

PDF Article
More Like This
Infrared spectroscopy of secondary organic aerosol precursors and investigation of the hygroscopicity of SOA formed from the OH reaction with guaiacol and syringol

Waed Ahmad, Cecile Coeur, Alexandre Tomas, Thomas Fagniez, Jean-Blaise Brubach, and Arnaud Cuisset
Appl. Opt. 56(11) E116-E122 (2017)

Analysis of pollutant chemistry in combustion by in situ pulsed photoacoustic laser diagnostics

Jari Stenberg, Rolf Hernberg, and Juha Vattulainen
Appl. Opt. 34(36) 8400-8408 (1995)

Quantification of solid-phase chemical reactions using the temperature-dependent terahertz pulsed spectroscopy, sum rule, and Arrhenius theory: thermal decomposition of α-lactose monohydrate

G. A. Komandin, K. I. Zaytsev, I. N. Dolganova, V. S. Nozdrin, S. V. Chuchupal, V. B. Anzin, and I. E. Spektor
Opt. Express 30(6) 9208-9221 (2022)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved