OSA's Digital Library

Applied Spectroscopy

Applied Spectroscopy

| PUBLISHED BY SAS — AVAILABLE FROM SAS AND OSA

  • Vol. 53, Iss. 6 — Jun. 1, 1999
  • pp: 619–627

Study of Fiber-Optic Probes for in Vivo Medical Raman Spectroscopy

Martin G. Shim, Brian C. Wilson, Eric Marple, and Michael Wach

Applied Spectroscopy, Vol. 53, Issue 6, pp. 619-627 (1999)


View Full Text Article

Acrobat PDF (578 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations
  • Export Citation/Save Click for help

Abstract

Recent reports indicate that useful diagnostic information can be obtained from ex vivo tissue by using near-infrared Raman spectroscopy. A fiber-optic-based Raman system has been constructed that can obtain spectra in vivo from tissue, typically in less than 30 s. The spectral details are limited by the fluorescence and Raman signal generated in the silica delivery and collection fibers. In this study, fiber-optic probes that are designed to suppress these confounding signals have been characterized and compared with a probe constructed of unfiltered silica fiber. These suppressing probes used a novel design with "in-the-tip" filters, which also had optimized light collection efficiency. The spatial point response functions of the fibers were measured in air, water, and a tissue-simulating, optically turbid medium. Spectra from rabbit tissues were also collected with these probes to demonstrate their performance.

Citation
Martin G. Shim, Brian C. Wilson, Eric Marple, and Michael Wach, "Study of Fiber-Optic Probes for in Vivo Medical Raman Spectroscopy," Appl. Spectrosc. 53, 619-627 (1999)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-53-6-619


Sort:  Journal  |  Reset

References

References are not available for this paper.

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited