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Applied Spectroscopy

Applied Spectroscopy

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  • Vol. 65, Iss. 9 — Sep. 1, 2011
  • pp: 1004–1008

Detection of Drugs of Abuse in Saliva by Surface-Enhanced Raman Spectroscopy (SERS)

Frank Inscore, Chetan Shende, Atanu Sengupta, Hermes Huang, and Stuart Farquharson

Applied Spectroscopy, Vol. 65, Issue 9, pp. 1004-1008 (2011)


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Abstract

Eighty drugs of abuse and metabolites were successfully measured by surface-enhanced Raman spectroscopy (SERS) using gold- and silver-doped sol-gels immobilized in glass capillaries. A method was developed that provided consistent detection of 50 ppb cocaine in saliva in a focused study. This general method was successfully applied to the detection of a number of additional drugs in saliva, such as amphetamine, diazepam, and methadone.

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Citation
Frank Inscore, Chetan Shende, Atanu Sengupta, Hermes Huang, and Stuart Farquharson, "Detection of Drugs of Abuse in Saliva by Surface-Enhanced Raman Spectroscopy (SERS)," Appl. Spectrosc. 65, 1004-1008 (2011)
http://www.opticsinfobase.org/as/abstract.cfm?URI=as-65-9-1004

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