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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 11 — Nov. 1, 2011
  • pp: 3047–3057

Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm

Simon Hyttel-Sorensen, Line C. Sorensen, Joan Riera, and Gorm Greisen  »View Author Affiliations

Biomedical Optics Express, Vol. 2, Issue 11, pp. 3047-3057 (2011)

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We compared absolute values of regional tissue hemoglobin saturation (StO2), reproducibility, and dynamic range of four different instruments on the forearm of adults. The sensors were repositioned 10 times on each subject. Dynamic range was estimated by exercise with subsequent arterial occlusion. Mean StO2 was 70.1% ± 6.7 with INVOS 5100, 69.4% ± 5.0 with NIRO 200 NX, 63.4% ± 4.5 with NIRO 300, and 60.8% ± 3.6 with OxyPrem. The corresponding reproducibility Sw was 5.4% (CI 4.4–6.9), 4.4% (CI 3.5–5.2), 4.1% (CI 3.3–4.9), and 2.7% (CI 2.2–3.2), respectively. The dynamic ranges ΔStO2 were 45.0%, 46.8%, 44.8%, and 27.8%, respectively. In conclusion, the three commercial NIRS instruments showed different absolute values, whereas reproducibility and dynamic range were quite similar.

© 2011 OSA

OCIS Codes
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(300.6190) Spectroscopy : Spectrometers

ToC Category:
Noninvasive Optical Diagnostics

Original Manuscript: August 24, 2011
Revised Manuscript: October 1, 2011
Manuscript Accepted: October 1, 2011
Published: October 6, 2011

Simon Hyttel-Sorensen, Line C. Sorensen, Joan Riera, and Gorm Greisen, "Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm," Biomed. Opt. Express 2, 3047-3057 (2011)

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