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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 4 — Apr. 1, 2011
  • pp: 858–870

Demonstration of remote optical measurement configuration that correlates to glucose concentration in blood

Yevgeny Beiderman, Raz Blumenberg, Nir Rabani, Mina Teicher, Javier Garcia, Vicente Mico, and Zeev Zalevsky  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 4, pp. 858-870 (2011)
http://dx.doi.org/10.1364/BOE.2.000858


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Abstract

An optical approach allowing the extraction and the separation of remote vibration sources has recently been proposed. The approach has also been applied for medical related applications as blood pressure and heart beats monitoring. In this paper we demonstrate its capability to monitor glucose concentration in blood stream. The technique is based on the tracking of temporal changes of reflected secondary speckle produced in human skin (wrist) when being illuminated by a laser beam. A temporal change in skin’s vibration profile generated due to blood pulsation is analyzed for estimating the glucose concentration. Experimental tests that were carried out in order to verify the proposed approach showed good match with the change of the glucose level at the positive slope stage as it was obtained from conventional reference measurement.

© 2011 OSA

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(280.0280) Remote sensing and sensors : Remote sensing and sensors

ToC Category:
Noninvasive Optical Diagnostics

History
Original Manuscript: November 1, 2010
Revised Manuscript: February 6, 2011
Manuscript Accepted: March 6, 2011
Published: March 14, 2011

Citation
Yevgeny Beiderman, Raz Blumenberg, Nir Rabani, Mina Teicher, Javier Garcia, Vicente Mico, and Zeev Zalevsky, "Demonstration of remote optical measurement configuration that correlates to glucose concentration in blood," Biomed. Opt. Express 2, 858-870 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-4-858


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