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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 2, Iss. 5 — May. 1, 2011
  • pp: 1218–1232

Complete complex conjugate resolved heterodyne swept-source optical coherence tomography using a dispersive optical delay line

Al-Hafeez Dhalla and Joseph A. Izatt  »View Author Affiliations


Biomedical Optics Express, Vol. 2, Issue 5, pp. 1218-1232 (2011)
http://dx.doi.org/10.1364/BOE.2.001218


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Abstract

Swept-source optical coherence tomography (SSOCT) provides a substantial sensitivity advantage over its time-domain counterpart, but suffers from a reduced imaging depth range due to sensitivity falloff and complex conjugate ambiguity. Heterodyne complex conjugate-resolved SSOCT (HCCR-SSOCT) has been previously demonstrated as a technique to completely resolve the complex conjugate ambiguity, effectively doubling the falloff limited imaging depth, without the reduction in imaging speed associated with other CCR techniques. However, previous implementations of this technique have employed expensive and lossy optical modulators to provide the required differential phase modulation. In this paper, we demonstrate the use of a dispersive optical delay line (D-ODL) as the reference arm of an OCT system to realize HCCR-SSOCT. This technique maintains the existing advantages of HCCR-SSOCT in that it completely resolves the complex conjugate artifact and does not reduce imaging speed, while conferring the additional advantages of being low cost, maintaining system sensitivity and resolution, not requiring any additional signal processing, and working at all wavelengths and imaging speeds. The D-ODL also allows for hardware correction of unbalanced dispersion in the reference and sample arm, adding further flexibility to system design. We demonstrate the technique using an SSOCT system operating at 100kHz with a central wavelength of 1040nm. Falloff measurements performed using a standard OCT configuration and the proposed D-ODL demonstrate a doubling of the effective imaging range with no sensitivity or resolution penalty. Feasibility of the technique for in vivo imaging was demonstrated by imaging the ocular anterior segments of healthy human volunteers.

© 2011 OSA

OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(230.4110) Optical devices : Modulators

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: February 25, 2011
Revised Manuscript: April 13, 2011
Manuscript Accepted: April 13, 2011
Published: April 15, 2011

Citation
Al-Hafeez Dhalla and Joseph A. Izatt, "Complete complex conjugate resolved heterodyne swept-source optical coherence tomography using a dispersive optical delay line," Biomed. Opt. Express 2, 1218-1232 (2011)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-2-5-1218


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