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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 1 — Jan. 1, 2012
  • pp: 86–103

Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model

Vedran Kajić, Marieh Esmaeelpour, Boris Považay, David Marshall, Paul L. Rosin, and Wolfgang Drexler  »View Author Affiliations


Biomedical Optics Express, Vol. 3, Issue 1, pp. 86-103 (2012)
http://dx.doi.org/10.1364/BOE.3.000086


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Abstract

A two stage statistical model based on texture and shape for fully automatic choroidal segmentation of normal and pathologic eyes obtained by a 1060 nm optical coherence tomography (OCT) system is developed. A novel dynamic programming approach is implemented to determine location of the retinal pigment epithelium/ Bruch’s membrane /choriocapillaris (RBC) boundary. The choroid–sclera interface (CSI) is segmented using a statistical model. The algorithm is robust even in presence of speckle noise, low signal (thick choroid), retinal pigment epithelium (RPE) detachments and atrophy, drusen, shadowing and other artifacts. Evaluation against a set of 871 manually segmented cross-sectional scans from 12 eyes achieves an average error rate of 13%, computed per tomogram as a ratio of incorrectly classified pixels and the total layer surface. For the first time a fully automatic choroidal segmentation algorithm is successfully applied to a wide range of clinical volumetric OCT data.

© 2011 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(100.3008) Image processing : Image recognition, algorithms and filters

ToC Category:
Image Processing

History
Original Manuscript: November 1, 2011
Revised Manuscript: December 8, 2011
Manuscript Accepted: December 8, 2011
Published: December 12, 2011

Citation
Vedran Kajić, Marieh Esmaeelpour, Boris Považay, David Marshall, Paul L. Rosin, and Wolfgang Drexler, "Automated choroidal segmentation of 1060 nm OCT in healthy and pathologic eyes using a statistical model," Biomed. Opt. Express 3, 86-103 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-1-86


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