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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 11 — Nov. 1, 2012
  • pp: 2720–2732

Optics InfoBase > Biomedical Optics Express > Volume 3 > Issue 11 > Page 2720

Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology

Stefan Zotter, Michael Pircher, Teresa Torzicky, Bernhard Baumann, Hirofumi Yoshida, Futoshi Hirose, Philipp Roberts, Markus Ritter, Christopher Schütze, Erich Götzinger, Wolfgang Trasischker, Clemens Vass, Ursula Schmidt-Erfurth, and Christoph K. Hitzenberger  »View Author Affiliations


Biomedical Optics Express, Vol. 3, Issue 11, pp. 2720-2732 (2012)
http://dx.doi.org/10.1364/BOE.3.002720


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Abstract

We present a novel spectral domain polarization sensitive OCT system (PS-OCT) that operates at an A-scan rate of 70 kHz and supports scan angles of up to 40° × 40°. The high-speed imaging allows the acquisition of up to 1024 × 250 A-scans per 3D scan, which, together with the large field of view, considerably increases the informative value of the images. To demonstrate the excellent performance of the new PS-OCT system, we imaged several healthy volunteers and patients with various diseases such as glaucoma, AMD, Stargardt’s disease, and albinism. The results are compared with clinically established methods such as scanning laser polarimetry and autofluorescence.

© 2012 OSA

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: June 21, 2012
Revised Manuscript: September 24, 2012
Manuscript Accepted: October 1, 2012
Published: October 3, 2012

Virtual Issues
BIOMED 2012 (2012) Biomedical Optics Express

Citation
Stefan Zotter, Michael Pircher, Teresa Torzicky, Bernhard Baumann, Hirofumi Yoshida, Futoshi Hirose, Philipp Roberts, Markus Ritter, Christopher Schütze, Erich Götzinger, Wolfgang Trasischker, Clemens Vass, Ursula Schmidt-Erfurth, and Christoph K. Hitzenberger, "Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology," Biomed. Opt. Express 3, 2720-2732 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-11-2720


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