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Distributed scanning volumetric SDOCT for motion corrected corneal biometryRyan P. McNabb, Francesco LaRocca, Sina Farsiu, Anthony N. Kuo, and Joseph A. Izatt »View Author Affiliations
Ryan P. McNabb,1,*
Francesco LaRocca,1
Sina Farsiu,2,1
Anthony N. Kuo,2
and Joseph A. Izatt1,2
1Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Box 90281, Durham, NC 27708, USA 2Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA *Corresponding author: ryan.mcnabb@duke.edu |
Biomedical Optics Express, Vol. 3, Issue 9, pp. 2050-2065 (2012)
http://dx.doi.org/10.1364/BOE.3.002050
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Abstract
We present a method, termed distributed scanning OCT (DSOCT), which reduces the effects of patient motion on corneal biometry utilizing current-generation clinically available spectral domain optical coherence tomography (SDOCT) systems. We first performed a pilot study of the power spectrum of normal patient axial eye motion based on repeated (M-mode) SDOCT. Using DSOCT to reduce the effects of patient motion, we conducted a preliminary patient study comparing the measured anterior and posterior corneal curvatures and the calculated corneal power to both corneal topography and Scheimpflug photography in normal subjects. The repeatability for the measured radius of curvature of both anterior and posterior surfaces as well as calculated corneal refractive power using DSOCT was comparable to those of both topography and Scheimpflug photography.
© 2012 OSA
OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(110.4153) Imaging systems : Motion estimation and optical flow
ToC Category:
Optical Coherence Tomography
History
Original Manuscript: May 21, 2012
Revised Manuscript: August 8, 2012
Manuscript Accepted: August 9, 2012
Published: August 10, 2012
Citation
Ryan P. McNabb, Francesco LaRocca, Sina Farsiu, Anthony N. Kuo, and Joseph A. Izatt, "Distributed scanning volumetric SDOCT for motion corrected corneal biometry," Biomed. Opt. Express 3, 2050-2065 (2012)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-3-9-2050
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- I. Grulkowski, M. Gora, M. Szkulmowski, I. Gorczynska, D. Szlag, S. Marcos, A. Kowalczyk, and M. Wojtkowski, “Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera,” Opt. Express17(6), 4842–4858 (2009). [CrossRef] [PubMed]
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- I. Grulkowski, M. Gora, M. Szkulmowski, I. Gorczynska, D. Szlag, S. Marcos, A. Kowalczyk, and M. Wojtkowski, “Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera,” Opt. Express17(6), 4842–4858 (2009). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, “Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography,” Arch. Ophthalmol.112(12), 1584–1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, “In vivo retinal imaging by optical coherence tomography,” Opt. Lett.18(21), 1864–1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991). [CrossRef] [PubMed]
- J. T. Holladay, W. E. Hill, and A. Steinmueller, “Corneal power measurements using scheimpflug imaging in eyes with prior corneal refractive surgery,” J. Refract. Surg.25(10), 862–868 (2009). [CrossRef] [PubMed]
- W. Drexler, C. K. Hitzenberger, A. Baumgartner, O. Findl, H. Sattmann, and A. F. Fercher, “Investigation of dispersion effects in ocular media by multiple wavelength partial coherence interferometry,” Exp. Eye Res.66(1), 25–33 (1998). [CrossRef] [PubMed]
- J. D. Ho, C. Y. Tsai, R. J. F. Tsai, L. L. Kuo, I. L. Tsai, and S. W. Liou, “Validity of the keratometric index: evaluation by the Pentacam rotating Scheimpflug camera,” J. Cataract Refract. Surg.34(1), 137–145 (2008). [CrossRef] [PubMed]
- J. T. Holladay, W. E. Hill, and A. Steinmueller, “Corneal power measurements using scheimpflug imaging in eyes with prior corneal refractive surgery,” J. Refract. Surg.25(10), 862–868 (2009). [CrossRef] [PubMed]
- M. Tang, L. Wang, D. D. Koch, Y. Li, and D. Huang, “Intraocular lens power calculation after previous myopic laser vision correction based on corneal power measured by Fourier-domain optical coherence tomography,” J. Cataract Refract. Surg.38(4), 589–594 (2012). [CrossRef] [PubMed]
- M. Tang, A. Chen, Y. Li, and D. Huang, “Corneal power measurement with Fourier-domain optical coherence tomography,” J. Cataract Refract. Surg.36(12), 2115–2122 (2010). [CrossRef] [PubMed]
- M. Tang, Y. Li, M. Avila, and D. Huang, “Measuring total corneal power before and after laser in situ keratomileusis with high-speed optical coherence tomography,” J. Cataract Refract. Surg.32(11), 1843–1850 (2006). [CrossRef] [PubMed]
- R. C. Lin, M. A. Shure, A. M. Rollins, J. A. Izatt, and D. Huang, “Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry,” Opt. Lett.29(1), 83–85 (2004). [CrossRef] [PubMed]
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Ophthalmology
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Opt. Express
- M. Zhao, A. N. Kuo, and J. A. Izatt, “3D refraction correction and extraction of clinical parameters from spectral domain optical coherence tomography of the cornea,” Opt. Express18(9), 8923–8936 (2010). [CrossRef] [PubMed]
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2012, Kuo, Biomed. Opt. Express
- M. Tang, L. Wang, D. D. Koch, Y. Li, and D. Huang, “Intraocular lens power calculation after previous myopic laser vision correction based on corneal power measured by Fourier-domain optical coherence tomography,” J. Cataract Refract. Surg.38(4), 589–594 (2012). [CrossRef] [PubMed]
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- R. F. Spaide, H. Koizumi, and M. C. Pozonni, “Enhanced depth imaging spectral-domain optical coherence tomography,” Am. J. Ophthalmol.146(4), 496–500 (2008). [CrossRef] [PubMed]
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- J. Otero-Millan, X. G. Troncoso, S. L. Macknik, I. Serrano-Pedraza, and S. Martinez-Conde, “Saccades and microsaccades during visual fixation, exploration, and search: foundations for a common saccadic generator,” J. Vis.8(14), 21, 1–18 (2008). [CrossRef] [PubMed]
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- V. Christopoulos, L. Kagemann, G. Wollstein, H. Ishikawa, M. L. Gabriele, M. Wojtkowski, V. Srinivasan, J. G. Fujimoto, J. S. Duker, D. K. Dhaliwal, and J. S. Schuman, “In vivo corneal high-speed, ultra high-resolution optical coherence tomography,” Arch. Ophthalmol.125(8), 1027–1035 (2007). [CrossRef] [PubMed]
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- C. K. S. Leung, W.-M. Chan, C. Y. Ko, S. I. Chui, J. Woo, M.-K. Tsang, and R. K. K. Tse, “Visualization of anterior chamber angle dynamics using optical coherence tomography,” Ophthalmology112(6), 980–984 (2005). [CrossRef] [PubMed]
- B. Seitz, A. Langenbucher, N. X. Nguyen, M. M. Kus, and M. Küchle, “Underestimation of intraocular lens power for cataract surgery after myopic photorefractive keratectomy,” Ophthalmology106(4), 693–702 (1999). [CrossRef] [PubMed]
- W. Drexler, C. K. Hitzenberger, A. Baumgartner, O. Findl, H. Sattmann, and A. F. Fercher, “Investigation of dispersion effects in ocular media by multiple wavelength partial coherence interferometry,” Exp. Eye Res.66(1), 25–33 (1998). [CrossRef] [PubMed]
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- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, “Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography,” Arch. Ophthalmol.112(12), 1584–1589 (1994). [CrossRef] [PubMed]
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- T. Olsen, “On the calculation of power from curvature of the cornea,” Br. J. Ophthalmol.70(2), 152–154 (1986). [CrossRef] [PubMed]
- R. W. Ditchburn and B. L. Ginsborg, “Involuntary eye movements during fixation,” J. Physiol.119(1), 1–17 (1953). [PubMed]
- F. Ratliff and L. A. Riggs, “Involuntary motions of the eye during monocular fixation,” J. Exp. Psychol.40(6), 687–701 (1950). [CrossRef] [PubMed]
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