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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 9 — Sep. 1, 2012
  • pp: 2087–2099

Polarized multispectral imaging in a rigid endoscope based on elastic light scattering spectroscopy

Ji Qi, Clement Barrière, Tobias C. Wood, and Daniel S. Elson  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 9, pp. 2087-2099 (2012)

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Elastic light scattering spectroscopy (LSS) is widely utilized to investigate cellular structures in cultured cells and various tissues. However, few imaging systems, especially endoscopic imaging systems, can implement LSS. It is the aim of this work to create a polarized multispectral imaging system based around a rigid endoscope to detect micrometer sized particles using LSS. The instrument first validated with different sized mono-disperse polystyrene microspheres, then an image is reconstructed based on LSS which shows the differentiation of different sized microspheres. Finally a preliminary experiment is conducted to demonstrate its capability to discriminate different types of cells.

© 2012 OSA

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(110.4234) Imaging systems : Multispectral and hyperspectral imaging
(290.5855) Scattering : Scattering, polarization

ToC Category:
Endoscopes, Catheters and Micro-Optics

Original Manuscript: June 18, 2012
Revised Manuscript: August 7, 2012
Manuscript Accepted: August 8, 2012
Published: August 13, 2012

Virtual Issues
BIOMED 2012 (2012) Biomedical Optics Express

Ji Qi, Clement Barrière, Tobias C. Wood, and Daniel S. Elson, "Polarized multispectral imaging in a rigid endoscope based on elastic light scattering spectroscopy," Biomed. Opt. Express 3, 2087-2099 (2012)

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