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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 3, Iss. 9 — Sep. 1, 2012
  • pp: 2121–2130

The influence of frontal sinus in brain activation measurements by near-infrared spectroscopy analyzed by realistic head models

Kazuki Kurihara, Hiroshi Kawaguchi, Takayuki Obata, Hiroshi Ito, Kaoru Sakatani, and Eiji Okada  »View Author Affiliations

Biomedical Optics Express, Vol. 3, Issue 9, pp. 2121-2130 (2012)

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Adequate modeling of light propagation in the head is important to predict the sensitivity of NIRS signal and the spatial sensitivity profile of source-detector pairs. The 3D realistic head models of which the geometry is based upon the anatomical images acquired by magnetic resonance imaging and x-ray computed tomography are constructed to investigate the influence of the frontal sinus on the NIRS signal and spatial sensitivity. Light propagation in the head is strongly affected by the presence of the frontal sinus. The light tends to propagate around the frontal sinus. The influence of the frontal sinus on the sensitivity of the NIRS signal to the brain activation is not consistent and depends on the depth of the frontal sinus, the optical properties of the superficial tissues and the relative position between the source-detector pair and the frontal sinus. The frontal sinus located in the shallow region of the skull tends to reduce the sensitivity of the NIRS signal while the deep frontal sinus can increase the sensitivity of the NIRS signal.

© 2012 OSA

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5280) Medical optics and biotechnology : Photon migration
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Optics of Tissue and Turbid Media

Original Manuscript: June 18, 2012
Revised Manuscript: July 29, 2012
Manuscript Accepted: July 29, 2012
Published: August 14, 2012

Virtual Issues
BIOMED 2012 (2012) Biomedical Optics Express

Kazuki Kurihara, Hiroshi Kawaguchi, Takayuki Obata, Hiroshi Ito, Kaoru Sakatani, and Eiji Okada, "The influence of frontal sinus in brain activation measurements by near-infrared spectroscopy analyzed by realistic head models," Biomed. Opt. Express 3, 2121-2130 (2012)

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