Optics InfoBase > Biomedical Optics Express > Volume 4 > Issue 1 > Page 105
|
Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapyDavid R. Busch, Regine Choe, Mark A. Rosen, Wensheng Guo, Turgut Durduran, Michael D. Feldman, Carolyn Mies, Brian J. Czerniecki, Julia Tchou, Angela DeMichele, Mitchell D. Schnall, and Arjun G. Yodh »View Author Affiliations
David R. Busch,1,*
Regine Choe,2
Mark A. Rosen,3
Wensheng Guo,4
Turgut Durduran,5
Michael D. Feldman,6
Carolyn Mies,6
Brian J. Czerniecki,7
Julia Tchou,7
Angela DeMichele,8
Mitchell D. Schnall,3
and Arjun G. Yodh1
1Dept. of Physics and Astronomy, University of Pennsylvania, 209 S. 33rd St., Philadelphia, PA 19104 USA 2Dept. of Biomedical Engineering, University of Rochester NY 14627 USA 3Dept. of Radiology, University of Pennsylvania, PA 19104 USA 4Dept. of Biostatistics, University of Pennsylvania, PA 19104 USA 5Institut de Ciències Fotòniques, Castelldefels, Barcelona Spain 6Dept. of Pathology and Laboratory Medicine, University of Pennsylvania, PA 19104 USA 7Dept. of Surgery, University of Pennsylvania, PA 19104 USA 8Depts. of Medicine (Hematology/Oncology) and Epidemiology, University of Pennsylvania, PA 19104 USA *Corresponding author: drbusch@sdf.org |
Biomedical Optics Express, Vol. 4, Issue 1, pp. 105-121 (2013)
http://dx.doi.org/10.1364/BOE.4.000105
View Full Text Article
Enhanced HTML 
Acrobat PDF (1700 KB)
Abstract
We introduce and demonstrate use of a novel, diffuse optical tomography (DOT) based breast cancer signature for monitoring progression of neoadjuvant chemotherapy. This signature, called probability of malignancy, is obtained by statistical image analysis of total hemoglobin concentration, blood oxygen saturation, and scattering coefficient distributions in the breast tomograms of a training-set population with biopsy-confirmed breast cancers. A pilot clinical investigation adapts this statistical image analysis approach for chemotherapy monitoring of three patients. Though preliminary, the study shows how to use the malignancy parameter for separating responders from partial-responders and demonstrates the potential utility of the methodology compared to traditional DOT quantification schemes.
© 2012 OSA
OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3830) Medical optics and biotechnology : Mammography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
ToC Category:
Optics in Cancer Research
History
Original Manuscript: September 11, 2012
Revised Manuscript: November 27, 2012
Manuscript Accepted: November 28, 2012
Published: December 14, 2012
Citation
David R. Busch, Regine Choe, Mark A. Rosen, Wensheng Guo, Turgut Durduran, Michael D. Feldman, Carolyn Mies, Brian J. Czerniecki, Julia Tchou, Angela DeMichele, Mitchell D. Schnall, and Arjun G. Yodh, "Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy," Biomed. Opt. Express 4, 105-121 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-1-105
Sort: Author | Year | Journal | Reset
References
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- R. Choe and T. Durduran, “Diffuse optical monitoring of the neoadjuvant breast cancer therapy,” IEEE J. Sel. Top. Quantum Electron.18, 1367–1386 (2012). [CrossRef]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- M. S. Pepe, The Statistical Evaluation of Medical Tests for Classification and Prediction (Oxford University Press, New York, 2003).
- N. E. Breslow, N. E. Day, and W. Davis, Statistical methods in cancer research (Vol. 1) The Analysis of Case control Studies, No. 32 in IARC Scientific Publications (International Agency for Research on Cancer, 1980).
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
Ahrendt, G.
Arlinghaus, L. R.
Arridge, S. R.
Bear, H. D.
Berry, D.
Bevilacqua, F.
Bhargava, R.
Blyschak, K.
Boas, D. A.
Boileau, J.
Bonaventura, M.
Bonnefoi, H.
Breslow, N. E.
Briest, S.
Busch, D. R.
Butler, J.
Butler, J. A.
Buzdar, A.
Cantanhede, G.
Carey, L.
Carpenter, C.
Carpenter, C. M.
Cerussi, A.
Cerussi, A. E.
Chance, B.
Cheang, M.
Chen, W.-P.
Choe, R.
Colleoni, M.
Compton, M.
Conant, E. F.
Conway-Dorsey, K.
Corlu, A.
Culver, J. P.
Czarnota, G.
Czerniecki, B. J.
Dang, H.
Davis, S.
Davis, W.
Day, N. E.
Dehghani, H.
DeMichele, A.
Denkert, C.
Dent, R.
Douek, M.
Doyley, M. M.
Durduran, T.
Durkin, A.
Eames, M.
Eiermann, W.
Enfield, L. C.
Esserman, L.
Falou, O.
Feldman, M. D.
Forero, J. A.
Fraker, D. L.
Froehlich, H. M.
Ghadyani, H.
Gibson, A. P.
Gore, J. C.
Gratton, E.
Gray, J.
Gunasekara, A.
Guo, W.
Hebden, J. C.
Hegde, P.
Hsiang, D.
Hwang, E.
Iradji, S.
Jackesz, R.
Jakubowski, D. B.
Jermyn, M.
Jiang, S.
Johnson, R.
Jong, R.
Kane, M.
Kaufman, P. A.
Kaufmann, M.
Kogel, C. A.
Konecky, S. D.
Kukreti, S.
Kurtzman, S. H.
Lee, K.
Lemon-Wong, S.
Lenburg, M.
Levy, M.
Li, X.
Li, Z.
Lilge, L.
Loibi, S.
Makris, A.
Mastanduno, M.
McGale, P.
McGuire, K.
McLaren, C.
Mehta, R.
Mehta, R. S.
Mies, C.
Miller, W.
Muffly, L. S.
Nioka, S.
Orel, S. G.
Pakalniskis, M. G.
Paulsen, K. D.
Pepe, M. S.
Perou, C.
Pierga, J.-Y.
Pogue, B. W.
Poplack, S. P.
Purushotham, A. D.
Putt, M. E.
Roblyer, D.
Rosen, M. A.
Rycroft, M.
Sadeghi-Naini, A.
Schnall, M. D.
Schneeweiss, A.
Schwab, M. C.
Schwartz, G. N.
Schweiger, M.
Semiglazov, V.
Shah, N.
Simick, M.
Simick, M. K.
Smith, D.
Soliman, H.
Song, X.
Soran, A.
Souchon, R.
Spayne, J.
Srinivasan, S.
Stearns, V.
Tanamai, V. W.
Tanamai, W.
Tannenbaum, S.
Tchou, J.
Toro-Burguete, J.
Tosteson, T. D.
Tromberg, B.
Tromberg, B. J.
Trudeau, M.
Ueda, S.
Untch, M.
von Minckwitz, G.
Welch, E. B.
Wells, W. A.
Westbroek, D.
Wilson, B.
Xu, C.
Yaffe, M.
Yalavarthy, P.
Yankeelov, T. E.
Yau, C.
Yodh, A. G.
Young, J.
Zhang, J.
Zhu, Q.
Zubovits, J.
Zuley, M.
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- N. E. Breslow, N. E. Day, and W. Davis, Statistical methods in cancer research (Vol. 1) The Analysis of Case control Studies, No. 32 in IARC Scientific Publications (International Agency for Research on Cancer, 1980).
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- R. Choe and T. Durduran, “Diffuse optical monitoring of the neoadjuvant breast cancer therapy,” IEEE J. Sel. Top. Quantum Electron.18, 1367–1386 (2012). [CrossRef]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- N. E. Breslow, N. E. Day, and W. Davis, Statistical methods in cancer research (Vol. 1) The Analysis of Case control Studies, No. 32 in IARC Scientific Publications (International Agency for Research on Cancer, 1980).
- N. E. Breslow, N. E. Day, and W. Davis, Statistical methods in cancer research (Vol. 1) The Analysis of Case control Studies, No. 32 in IARC Scientific Publications (International Agency for Research on Cancer, 1980).
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- R. Choe and T. Durduran, “Diffuse optical monitoring of the neoadjuvant breast cancer therapy,” IEEE J. Sel. Top. Quantum Electron.18, 1367–1386 (2012). [CrossRef]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- M. S. Pepe, The Statistical Evaluation of Medical Tests for Classification and Prediction (Oxford University Press, New York, 2003).
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
Acad. Rad.
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
Ann. Oncol.
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
Ann. Surg. Oncol.
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
Appl. Opt.
- X. Song, B. W. Pogue, S. Jiang, M. M. Doyley, H. Dehghani, T. D. Tosteson, and K. D. Paulsen, “Automated region detection based on the contrast-to-noise ratio in near-infrared tomography,” Appl. Opt.43, 1053–1062 (2004). [CrossRef] [PubMed]
Breast Cancer Res.
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
Breast Cancer Res. Treat.
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
Clin. Cancer Res.
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
Commun. Numer. Meth. Eng.
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
IEEE J. Sel. Top. Quantum Electron.
- R. Choe and T. Durduran, “Diffuse optical monitoring of the neoadjuvant breast cancer therapy,” IEEE J. Sel. Top. Quantum Electron.18, 1367–1386 (2012). [CrossRef]
J. Biomed. Opt.
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
J. Oncol.
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
Med. Phys.
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
Neoplasia
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
Philos. Trans. R. Soc. A
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
Proc. Natl. Acad. Sci.
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
Radiology
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
Technol. Cancer Res. Treat.
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
Trans. Onc.
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
Other
- M. Jermyn, B. W. Pogue, H. Ghadyani, S. Davis, M. Mastanduno, and H. Dehghani, “A user-enabling visual workflow for near-infrared light transport modeling in tissue,” in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2012), paper BW1A.7.
- M. S. Pepe, The Statistical Evaluation of Medical Tests for Classification and Prediction (Oxford University Press, New York, 2003).
- N. E. Breslow, N. E. Day, and W. Davis, Statistical methods in cancer research (Vol. 1) The Analysis of Case control Studies, No. 32 in IARC Scientific Publications (International Agency for Research on Cancer, 1980).
2012, Choe, IEEE J. Sel. Top. Quantum Electron.
- R. Choe and T. Durduran, “Diffuse optical monitoring of the neoadjuvant breast cancer therapy,” IEEE J. Sel. Top. Quantum Electron.18, 1367–1386 (2012). [CrossRef]
- O. Falou, H. Soliman, A. Sadeghi-Naini, S. Iradji, S. Lemon-Wong, J. Zubovits, J. Spayne, R. Dent, M. Trudeau, J. Boileau, and , “Diffuse optical spectroscopy evaluation of treatment response in women with locally advanced breast cancer receiving neoadjuvant chemotherapy,” Trans. Onc.5, 238–246 (2012).
- D. Roblyer, S. Ueda, A. Cerussi, W. Tanamai, A. Durkin, R. Mehta, D. Hsiang, J. A. Butler, C. McLaren, W.-P. Chen, and B. Tromberg, “Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment.” Proc. Natl. Acad. Sci.108, 14626–14631 (2011). [CrossRef] [PubMed]
- L. C. Enfield, G. Cantanhede, D. Westbroek, M. Douek, A. D. Purushotham, J. C. Hebden, and A. P. Gibson, “Monitoring the response to primary medical therapy for breast cancer using three-dimensional time-resolved optical mammography.” Technol. Cancer Res. Treat.10, 533–547 (2011). [PubMed]
- L. Esserman, D. Berry, M. Cheang, C. Yau, C. Perou, L. Carey, A. DeMichele, J. Gray, K. Conway-Dorsey, M. Lenburg, and , “Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657),” Breast Cancer Res. Treat.30, 3242–3249 (2011).
- K. McGuire, J. Toro-Burguete, H. Dang, J. Young, A. Soran, M. Zuley, R. Bhargava, M. Bonaventura, R. Johnson, and G. Ahrendt, “MRI staging after neoadjuvant chemotherapy for breast cancer: Does tumor biology affect accuracy?” Ann. Surg. Oncol.18, 3149–3154 (2011). [CrossRef] [PubMed]
- M. G. Pakalniskis, W. A. Wells, M. C. Schwab, H. M. Froehlich, S. Jiang, Z. Li, T. D. Tosteson, S. P. Poplack, P. A. Kaufman, B. W. Pogue, and K. D. Paulsen, “Tumor angiogenesis change estimated by using diffuse optical spectroscopic tomography: demonstrated correlation in women undergoing neoadjuvant chemotherapy for invasive breast cancer?” Radiology259, 365–374 (2011). [CrossRef] [PubMed]
- A. E. Cerussi, V. W. Tanamai, D. Hsiang, J. Butler, R. S. Mehta, and B. J. Tromberg, “Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy.” Philos. Trans. R. Soc. A369, 4512–4530 (2011). [CrossRef]
- L. R. Arlinghaus, X. Li, M. Levy, D. Smith, E. B. Welch, J. C. Gore, and T. E. Yankeelov, “Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy,” J. Oncol.919620, 1–17 (2010). [CrossRef]
- H. Soliman, A. Gunasekara, M. Rycroft, J. Zubovits, R. Dent, J. Spayne, M. Yaffe, and G. Czarnota, “Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer,” Clin. Cancer Res.16, 2605–2614 (2010). [CrossRef] [PubMed]
- D. R. Busch, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, and A. G. Yodh, “Computer aided automatic detection of malignant lesions in diffuse optical mammography,” Med. Phys.37, 1840–1849 (2010). [CrossRef] [PubMed]
- R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, and A. G. Yodh, “Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography,” J. Biomed. Opt.14, 024020 (2009). [CrossRef] [PubMed]
- H. Dehghani, M. Eames, P. Yalavarthy, S. Davis, S. Srinivasan, C. Carpenter, B. W. Pogue, and K. D. Paulsen, “Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction,” Commun. Numer. Meth. Eng.25, 711–732 (2009). [CrossRef]
- S. Jiang, B. W. Pogue, C. M. Carpenter, S. P. Poplack, W. A. Wells, C. A. Kogel, J. A. Forero, L. S. Muffly, G. N. Schwartz, K. D. Paulsen, and P. A. Kaufman, “Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.” Radiology252, 551–560 (2009). [CrossRef] [PubMed]
- Q. Zhu, S. Tannenbaum, P. Hegde, M. Kane, C. Xu, and S. H. Kurtzman, “Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization.” Neoplasia10, 1028–1040 (2008). [PubMed]
- B. J. Tromberg, B. W. Pogue, K. D. Paulsen, A. G. Yodh, D. A. Boas, and A. E. Cerussi, “Assessing the future of diffuse optical imaging technologies for breast cancer management,” Med. Phys.35, 2443–2451 (2008). [CrossRef] [PubMed]
- M. Kaufmann, G. von Minckwitz, H. D. Bear, A. Buzdar, P. McGale, H. Bonnefoi, M. Colleoni, C. Denkert, W. Eiermann, R. Jackesz, A. Makris, W. Miller, J.-Y. Pierga, V. Semiglazov, A. Schneeweiss, R. Souchon, V. Stearns, M. Untch, and S. Loibi, “Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006,” Ann. Oncol.18, 1927–34 (2007). [CrossRef] [PubMed]
- A. Cerussi, D. Hsiang, N. Shah, R. Mehta, A. Durkin, J. Butler, and B. J. Tromberg, “Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy.” Proc. Natl. Acad. Sci.104, 4014–4019 (2007). [CrossRef] [PubMed]
- S. Kukreti, A. Cerussi, B. Tromberg, and E. Gratton, “Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra,” J. Biomed. Opt.12, 020509–020509–3(2007). [CrossRef] [PubMed]
- B. J. Tromberg, A. Cerussi, N. Shah, M. Compton, A. Durkin, D. Hsiang, J. Butler, and R. Mehta, “Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.” Breast Cancer Res.7, 279–285 (2005). [CrossRef]
- B. Chance, S. Nioka, J. Zhang, E. F. Conant, E. Hwang, S. Briest, S. G. Orel, M. D. Schnall, and B. J. Czerniecki, “Breast cancer detection based on incremental biochemical and physiological properties of breast cancers a six-year, two-site study,” Acad. Rad.12, 925–933 (2005). [CrossRef]
- M. K. Simick, R. Jong, B. Wilson, and L. Lilge, “Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk.” J. Biomed. Opt.9, 794–803 (2004). [CrossRef] [PubMed]
- K. Blyschak, M. Simick, R. Jong, and L. Lilge, “Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value,” Med. Phys.31, 1398–1414 (2004). [CrossRef] [PubMed]
- D. B. Jakubowski, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, “Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study,” J. Biomed. Opt.9, 230–238 (2004). [CrossRef] [PubMed]
Cited By |
 Alert me when this paper is cited |
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.
Related Journal Articles 
- Spectroscopic Diffuse Optical Tomography for the Quantitative Assessment of Hemoglobin Concentration and Oxygen Saturation in Breast Tissue (AO)
- Instrumentation and Calibration Protocol for Imaging Dynamic Features in Dense-Scattering Media by Optical Tomography (AO)
- Monitoring recovery after laser surgery of the breast with optical tomography: a case study (AO)
- Initial results of in vivo non-invasive cancer imaging in the human breast using near-infrared photoacoustics (OE)
- Seven-wavelength time-resolved optical mammography extending beyond 1000 nm for breast collagen quantification (OE)
Related Conference Papers
- Pump-Probe Melanoma Imaging: Applications to High-Resolution and In-Vivo Microscopy
- Pump-Probe Melanoma Imaging: Applications to High-Resolution and In-Vivo Microscopy
- Pump-probe Microscopy Captures Cellular Detail of Melanoma In-vivo
- Computer Aided Monitoring of Neoadjuvant Chemotherapy for Breast Cancer
- Microvascular Blood Flow Changes in Human Breast During Simulated Mammography
« Previous Article | Next Article »
OSA is a member of 
For optimal display we recommend the following web browsers:
- Firefox 11+
- Google Chrome 17+
- Internet Explorer 9+
- Safari 5+