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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 3 — Mar. 1, 2013
  • pp: 466–480

Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation

Yilei Shao, Aizhu Tao, Hong Jiang, Meixiao Shen, Jianguang Zhong, Fan Lu, and Jianhua Wang  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 3, pp. 466-480 (2013)
http://dx.doi.org/10.1364/BOE.4.000466


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Abstract

We demonstrated a novel approach of imaging the anterior segment including the ciliary muscle using combined and synchronized two spectral domain optical coherence tomography devices (SD-OCT). In one SD-OCT, a Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera and an alternating reference arm was used to image the anterior segment from the cornea to the lens. Another SD-OCT for imaging the ciliary muscle was equipped with a light source with a center wavelength of 1,310 nm and a bandwidth of 75 nm. Repeated measurements were performed under relaxed and 4.00 D accommodative stimulus states in six eyes from 6 subjects. We also imaged dynamic changes in the anterior segment in one eye during accommodation. The biometry of the anterior segment and the ciliary muscle was obtained. The combined system appeared to be capable to simultaneously real-time image the biometry of the anterior segment, including the ciliary muscle, in vivo during accommodation.

© 2013 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices
(330.7322) Vision, color, and visual optics : Visual optics, accommodation

ToC Category:
Ophthalmology Applications

History
Original Manuscript: December 10, 2012
Revised Manuscript: February 14, 2013
Manuscript Accepted: February 18, 2013
Published: February 21, 2013

Citation
Yilei Shao, Aizhu Tao, Hong Jiang, Meixiao Shen, Jianguang Zhong, Fan Lu, and Jianhua Wang, "Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation," Biomed. Opt. Express 4, 466-480 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-3-466


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