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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 4, Iss. 4 — Apr. 1, 2013
  • pp: 520–530

In vivo measurement of mid-infrared light scattering from human skin

Anna P. M. Michel, Sabbir Liakat, Kevin Bors, and Claire F. Gmachl  »View Author Affiliations


Biomedical Optics Express, Vol. 4, Issue 4, pp. 520-530 (2013)
http://dx.doi.org/10.1364/BOE.4.000520


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Abstract

Two mid-infrared light sources, a broadband source from a Fourier Transform Infrared Spectrometer (FTIR) and a pulsed Quantum Cascade (QC) Laser, are used to measure angle-resolved backscattering in vivo from human skin across a broad spectral range. Scattering profiles measured using the FTIR suggest limited penetration of the light into the skin, with most of the light interacting with the stratum corneum layer of the epidermis. Scattering profiles from the QC laser show modulation patterns with angle suggesting interaction with scattering centers in the skin. The scattering is attributed to interaction of the laser light with components such as collagen fibers and capillaries in the dermis layer of the skin.

© 2013 OSA

OCIS Codes
(170.6930) Medical optics and biotechnology : Tissue
(290.5820) Scattering : Scattering measurements
(140.5965) Lasers and laser optics : Semiconductor lasers, quantum cascade

ToC Category:
Optics of Tissue and Turbid Media

History
Original Manuscript: December 6, 2012
Revised Manuscript: January 18, 2013
Manuscript Accepted: February 15, 2013
Published: March 4, 2013

Citation
Anna P. M. Michel, Sabbir Liakat, Kevin Bors, and Claire F. Gmachl, "In vivo measurement of mid-infrared light scattering from human skin," Biomed. Opt. Express 4, 520-530 (2013)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-4-4-520


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