OSA's Digital Library

Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 7 — Jul. 1, 2014
  • pp: 2145–2156

Dynamic light scattering from pulsatile flow in the presence of induced motion artifacts

M. Nemati, C. N. Presura, H. P. Urbach, and N. Bhattacharya  »View Author Affiliations

Biomedical Optics Express, Vol. 5, Issue 7, pp. 2145-2156 (2014)

View Full Text Article

Enhanced HTML    Acrobat PDF (9871 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Continuous health monitoring has become a major theme of our aging society. Portable devices play an important role here. Many optical portable devices are susceptible to motion induced artifacts. We have performed an experimental study for detection of fluid pulsation based on multi-exposure speckle images, in presence of motion induced artifacts. Induced motion of a wide range of frequencies and amplitudes were generated to resemble sensor motion with respect to skin. The data was analyzed using speckle contrast and correlation. We concluded that both techniques have their own advantages, depending on the measurement configuration. A study of angles between illumination and detection revealed that larger angles yields better signal. Shorter exposure time was more successful in extracting the signal. We also performed in-vivo measurements that agree with the in-vitro case. We also show that a minimum collection of two pixels from the speckle image is sufficient to extract relevant results.

© 2014 Optical Society of America

OCIS Codes
(100.0100) Image processing : Image processing
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(230.0230) Optical devices : Optical devices
(290.0290) Scattering : Scattering

ToC Category:
Speckle Imaging and Diagnostics

Original Manuscript: February 7, 2014
Revised Manuscript: April 2, 2014
Manuscript Accepted: April 4, 2014
Published: June 10, 2014

M. Nemati, C. N. Presura, H. P. Urbach, and N. Bhattacharya, "Dynamic light scattering from pulsatile flow in the presence of induced motion artifacts," Biomed. Opt. Express 5, 2145-2156 (2014)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. D. A. Boas and A. K. Dunn, “Laser speckle contrast imaging in biomedical optics,” J. Biomed. Opt.15, 011109 (2010). [CrossRef] [PubMed]
  2. A. K. Dunn, “Laser speckle contrast imaging of cerebral blood flow,” Ann. Biomed. Eng.40, 367–377 (2012). [CrossRef]
  3. M. Nemati, L. Wei, M. G. Zeitouny, M. Stijnen, S. van Tuijl, N. Bhattacharya, and H. P. Urbach, “Laser speckle analysis of flow in presence of static scatterers,” Proc. SPIE8413, 84131D (2012). [CrossRef]
  4. D. Briers, D. D. Duncan, E. Hirst, S. J. Kirkpatrick, M. Larsson, W. Steenbergen, T. Stromberg, and O. B. Thompson, “Laser speckle contrast imaging: theoretical and practical limitations,” J. Biomed. Opt.18, 66018 (2013). [CrossRef]
  5. M. Nemati, R. W. C. G. R. Wijshoff, J. M. a. Stijnen, S. van Tuijl, J. W. M. Bergmans, N. Bhattacharya, and H. P. Urbach, “Laser-speckle-based detection of fluid pulsation in the presence of motion artifacts: in vitro and in vivo study,” Opt. Lett.38, 5334–5337 (2013). [CrossRef] [PubMed]
  6. M. Vegfors, L.-G. Lindberg, P. Å. Öberg, and C. Lennmarken, “Accuracy of pulse oximetry at various haematocrits and during haemolysis in anin vitro model,” Med. Biol. Eng. Comput.31, 135–141 (1993). [CrossRef] [PubMed]
  7. A. G. Gilman, “G proteins: transducers of receptor-generated signals,” Annu. Rev. Biochem.56, 615–649 (1987). [CrossRef] [PubMed]
  8. M. Michalski, V. Briard, and F. Michel, “Optical parameters of milk fat globules for laser light scattering measurements,” Lait81, 787–796 (2001). [CrossRef]
  9. R. F. Bonner, R. Nossal, S. Havlin, and G. H. Weiss, “Model for photon migration in turbid biological media,” J. Opt. Soc. Am. A4, 423–432 (1987). [CrossRef] [PubMed]
  10. P. Shi, V. A. Peris, A. Echiadis, J. Zheng, Z. Yisheng, P. Y. S. Cheang, and S. Hu, “Non-contact reflection photo-plethysmography towards effective human physiological monitoring,” J. Med. Biol. Eng.30, 161–167 (2009).
  11. J. D. Briers and S. Webster, “Quasi real-time digital version of single-exposure speckle photography for full-field monitoring of velocity or flow fields,” Opt. Commun.116, 36–42 (1995). [CrossRef]
  12. M. Draijer, E. Hondebrink, T. van Leeuwen, and W. Steenbergen, “Review of laser speckle contrast techniques for visualizing tissue perfusion,” Lasers. Med. Sci.24, 639–651 (2009). [CrossRef]
  13. A.F. Fercher and J.D. Briers, “Flow visualization by means of single exposure speckle photography,” Opt. Commun.37, 326–330 (1981). [CrossRef]
  14. R. Bandyopadhyay, A. S. Gittings, S. S. Suh, P. K. Dixon, and D. J. Durian, “Speckle-visibility spectroscopy: A tool to study time-varying dynamics,” Rev. Sci. Instrum.76, 093110 (2005). [CrossRef]
  15. K. Schatzel, “Noise on photon correlation data. I. Autocorrelation functions,” Quantum Opt.2, 287–305 (1990). [CrossRef]
  16. D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A14, 192 (1997). [CrossRef]
  17. B. J. Berne and R. Pecora, Dynamic Light Scattering : With Applications to Chemistry, Biology, and Physics (Dover Publications, 2000), unabridged ed.
  18. P. A. Bandettini, A. Jesmanowicz, E. C. Wong, and J. S. Hyde, “Processing strategies for time-course data sets in functional MRI of the human brain,” Magn. Reson. Med. Sci.30, 161–173 (1993). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited