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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 8 — Aug. 1, 2014
  • pp: 2791–2797

Single camera imaging system for color and near-infrared fluorescence image guided surgery

Zhenyue Chen, Nan Zhu, Shaun Pacheco, Xia Wang, and Rongguang Liang  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 8, pp. 2791-2797 (2014)
http://dx.doi.org/10.1364/BOE.5.002791


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Abstract

Near-infrared (NIR) fluorescence imaging systems have been developed for image guided surgery in recent years. However, current systems are typically bulky and work only when surgical light in the operating room (OR) is off. We propose a single camera imaging system that is capable of capturing NIR fluorescence and color images under normal surgical lighting illumination. Using a new RGB-NIR sensor and synchronized NIR excitation illumination, we have demonstrated that the system can acquire both color information and fluorescence signal with high sensitivity under normal surgical lighting illumination. The experimental results show that ICG sample with concentration of 0.13 μM can be detected when the excitation irradiance is 3.92 mW/cm2 at an exposure time of 10 ms.

© 2014 Optical Society of America

OCIS Codes
(100.2980) Image processing : Image enhancement
(110.0110) Imaging systems : Imaging systems
(110.2970) Imaging systems : Image detection systems
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(300.2530) Spectroscopy : Fluorescence, laser-induced

ToC Category:
Clinical Instrumentation

History
Original Manuscript: May 20, 2014
Revised Manuscript: July 17, 2014
Manuscript Accepted: July 19, 2014
Published: July 25, 2014

Citation
Zhenyue Chen, Nan Zhu, Shaun Pacheco, Xia Wang, and Rongguang Liang, "Single camera imaging system for color and near-infrared fluorescence image guided surgery," Biomed. Opt. Express 5, 2791-2797 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-8-2791


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