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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 5, Iss. 9 — Sep. 1, 2014
  • pp: 2963–2977

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

Wolfgang Wieser, Wolfgang Draxinger, Thomas Klein, Sebastian Karpf, Tom Pfeiffer, and Robert Huber  »View Author Affiliations


Biomedical Optics Express, Vol. 5, Issue 9, pp. 2963-2977 (2014)
http://dx.doi.org/10.1364/BOE.5.002963


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Abstract

We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin.

© 2014 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(140.3600) Lasers and laser optics : Lasers, tunable
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: May 23, 2014
Revised Manuscript: June 24, 2014
Manuscript Accepted: June 25, 2014
Published: August 6, 2014

Virtual Issues
August 22, 2014 Spotlight on Optics

Citation
Wolfgang Wieser, Wolfgang Draxinger, Thomas Klein, Sebastian Karpf, Tom Pfeiffer, and Robert Huber, "High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s," Biomed. Opt. Express 5, 2963-2977 (2014)
http://www.opticsinfobase.org/boe/abstract.cfm?URI=boe-5-9-2963


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