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Biomedical Optics Express

Biomedical Optics Express

  • Editor: Joseph A. Izatt
  • Vol. 1, Iss. 1 — Aug. 2, 2010
  • pp: 268–277

Signal attenuation and box-counting fractal analysis of optical coherence tomography images of arterial tissue

Dan P. Popescu, Costel Flueraru, Youxin Mao, Shoude Chang, and Michael G. Sowa  »View Author Affiliations

Biomedical Optics Express, Vol. 1, Issue 1, pp. 268-277 (2010)

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The sensitivity of optical coherence tomography images to sample morphology is tested by two methods. The first method estimates the attenuation of the OCT signal from various regions of the probed tissue. The second method uses a box-counting algorithm to calculate the fractal dimensions in the regions of interest identified in the images. Although both the attenuation coefficient as well as the fractal dimension correlate very well with the anatomical features of the probed samples; the attenuation method provides a better sensitivity. Two types of samples are used in this study: segments of arteries collected from atherosclerosis–prone Watanabe rabbits (WHHL-MI) and healthy segments of porcine coronary arteries.

© 2010 OSA

OCIS Codes
(030.5770) Coherence and statistical optics : Roughness
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6935) Medical optics and biotechnology : Tissue characterization

ToC Category:
Optical Coherence Tomography

Original Manuscript: June 1, 2010
Revised Manuscript: July 9, 2010
Manuscript Accepted: July 20, 2010
Published: July 26, 2010

Dan P. Popescu, Costel Flueraru, Youxin Mao, Shoude Chang, and Michael G. Sowa, "Signal attenuation and box-counting
fractal analysis of optical coherence
tomography images of arterial tissue," Biomed. Opt. Express 1, 268-277 (2010)

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